Work highlighted on cover page

Jorrnal Publications

• Musa, M. M.* “Alcohol Dehydrogenases with anti-Prelog Stereopreference in Synthesis of Enantiopure Alcohols”, ChemistryOpen, 2022, e202100251.

• Nzila, A.*; Musa, M. M. “Current knowledge and future challenges on bacterial degradation of the highly complex petroleum product asphaltenes and resins” Frontiers in Environmental Science 2021, 6, 13261-13264.

• Musa, M. M.*; Vieille, C.; Phillips, R. S. “Secondary alcohol dehydrogenases from Thermoanaerobacter pseudoethanolicus and Thermoanaerobacter brockii as robust catalysts” ChemBioChem 2021, 22, 1884-1893.

• Nzila, A.*; Musa, M. M.; Sankara, S.; Al-Momani, M.; Li, Q. “Degradation of benzo[a]pyrene by halophilic bacterium strain of Staphylococcus haemoliticus” PLOS ONE, 2021, 16, e0247723.

• Nzila, A.*, Musa M. M. “Current status of and future perspectives in bacterial degradation of benzo[a]pyrene” International Journal of Environmental Research and Public Health 2021, 8, 262.

• Nafiu, S.; Takahashi, M.; Takahashi, E.; Hamdan, S. M.; Musa, M. M.* “Simultaneous cyclic deracemisation and stereoinversion of alcohols using orthogonal biocatalytic oxidation and reduction reactions”. Catalysis Science & Technology 2020, 10, 8213–8218.

• Nafiu, S.; Takahashi, M.; Takahashi, E.; Hamdan, S. M.; Musa, M. M.* “Deracemization and Stereoinversion of Alcohols Using Two Mutants of Secondary Alcohol Dehydrogenase from Thermoanaerobacter pseudoethanolicus” European Journal of Organic Chemistry 2020, 4750–4754.

• Musa, M. M.* “Enzymatic racemization of alcohols and amines: An approach for bi-enzymatic dynamic kinetic resolution” Chirality, 2020, 32, 147–157.

• Musa, M. M.*; Hollmann, F.*; Mutti, F.* “Synthesis of enantiomerically pure alcohols and amines via deracemization methods” Catalysis Science & Technology, 2019, 9, 5487-5487.  Selected as Catalysis Science & Technology Hot Article. Featured as the Cover Page of Catalysis Science & Technology 20/2019.

• Musa, M. M.*; Karume, I.; Takahashi; Hamdan, S. M.; Ullah, N. "Stereoinversion of R-configured secondary alcohols using a single enzymatic approach" ChemistrySelect 2018, 3, 10205-10208.

• Nzila, A.; Ortega, C.; Musa, M. M.; Sankara, S.; Chanbasha, B.; Li, Q. X. "Pyrene biodegradation and proteomic analysis in Achromobacter xylosoxidans, PY4 strain" International Biodegradation & Bioremediation, 2018, 130, 40-47.

• Musa, M. M.*; Bsharat, O.; Karume, I.; Vieille, C.; Takahashi, M.; Hamdan, S. "Expanding the substrate specificity of Thermoanaerobacter pseudoethanolicus alcohol dehydrogenase by a dual site mutation" European Journal of Organic Chemistry, 2018, 2018 (6), 798-805.

• Budiyanto, F.; Thukair, A.; Al-Momani, M.; Musa M. M.; Nzila, A. "Characterization of halophilic bacteria cabable of efficiently biodegrading the high molecular weight polycyclic aromatic hydrocarbon pyrene" Environmental Engineering Science, 2018, 44, 43-54.

• Nzila, A.*; Sankara, S.; Al-Momani, M.; Musa, M. M. “Isolation and characterization of phenanthrene and anthracene biodegrading bacterial consortia” Archives of Environmental Protection, 2018, 44, 43–54.

• Bsharat, O.; Musa M. M.*; Oladepo, S.; Takahashi, M.; Vieille, C.; Hamdan, S. M. "Asymmetric reduction of substituted 2-tetralones by Thermoanaerobacter pseudoethanolicus secondary alcohol dehdrogense" ChemCatChem, 2017, 9, 1487-1493.

• Sulaiman, A. A.; Omer, K. H.; Kawde, A.; Wazeer, M. I.; Altaf, M.; Musa, M. M.; Ahmad, S.; Isab, A. A.* “Spectroscopic and electrochemical studies of the interaction of some Gold(III) complexes with biologically relevant thiones” International Journal of Chemical Kinetics 2018, 50, 178–187.

• Nzila, A.*; Sankara, S.; Al-Momani, M.; Musa, M. M. “Isolation and characterization of phenanthrene and anthracene biodegrading bacterial consortia” Archives of Environmental Protection, 2018, 44, 43–54.

• Alenaizan, A.; Al-Basheer, W.; Musa, M. M. "Solvent, temperature and concentration effects on the optical rotatory dispersion of (R)-3-methylcyclohexanone" Journal of Molecular Structure, 2017, 1130, 19-25.

• Ali, M., Musa, M. M.; Alfadul, S.; Al-Sobayel, K. "Consequences of adding gum Arabic as a cryoprotectant on motility and viability of frozen stallion semen" Cryobiology 2017, 79, 21-28.

• Omer, K. H.; Suleiman, A. A.; Al-Mohsin, H.; Kawdi, A.; Altaf, M.; Wazeer, M. I.; Ahmad, S.; Musa, M. M.; Isab, A. A. "Study of interaction of anti-cancer complexes with biologically important thiols using NMR, UV-Vis, and electrochemistry" International Journal of Chemical Kinetics 2017, 49, 387-397.

• Karume, I.; Musa, M. M.*; Bsharat, O.; Takahashi, M.; Hamdan, S. M.; El Ali B. "Dual enzymatic dynamic kinetic resolution by Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase" RSC Advances, 2016, 6, 96616-96622.

• Karume, I.; Masateru, T.; Hamdan S. M.; Musa, M. M.* "Deracemization of Secondary alcohols using a single alcohol dehydrogenase" ChemCatChem 2016, 8, 1459-1463. Featured as the back cover of ChemCatChem 8/2016.

•  Nzila, A.; Thukair, A.; Sankara, S.; Chanbasha, B.; Musa M. M. " Isolation and characterization of naphthalene biodegradating Methylobacterium radiotolerans bacterium from the Eastern Coastline of the Kingdom of Saudi Arabia" Archives of Environmental Protection, 2016, 42, 25-32.

•  Musa, M. M.*; Patel, J. M.; Nealon, C. M.; Kim, C. S.; Phillips, R. S.; Karume, I. "Thermoanaerobacter ethanolicus Secondary alcohol dehydrogenase mutants with improved racemization activity" Journal of Molecular Catalysis B: Enzymatic 2015, 115, 155-159.

• Nealon, C. M.; Musa, M. M.; Patel, J. M.; Phillips, R. S."Controlling substrate specificity and stereospecificity of alcohol dehydrogenases" ACS catalysis 2015, 5, 2100-2114.

•  Patel, J. M.; Musa M. M.; Rodriguez, D. A.; Sutton D. A.; Popik, V. V.; Phillips, R. S. "Mutation of Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase at Trp-110 affects stereoselectivity of aromatic ketone reduction" Organic & Biomolecular Chemistry 2014, 12, 5905-5910.

•  Musa, M. M.*; Phillips, R. S.; Laivenieks, M.; Vieille, C.; Takahashi; M.; Hamdan, S. M. "Racemization of enantiopure secondary alcohols by Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase" Organic & Biomolecular Chemistry 2013, 11, 2911-2915.
  Highlighted in Hot off the press (Nat. Prod. Rep., 2013, 30, 760)  

•  Musa, M. M.; Phillips, R. S. "Recent advances in alcohol dehydrogenase-catalyzed asymmetric production of hydrophobic alcohols" Catalysis Science &Technology 2011, 1, 1311-1323.
  Selected as a hot article

•  Gaffarogullari, E. C., Masterson, L., Metcalfe, E.; Traaseth, N.; Balatri, E.; Musa, M. M.; Mullen, D.; Distefano, M. D.; Veglia, G. "A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes" Journal of Molecular Biology 2011, 411 (4) 823-836.

•  Musa, M. M.; Lott, N.; Laivenieks, M.; Watanabe, L.; Vieille, C.; Phillips, R. S. "A single point mutation reverses the enantiopreference of Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase" ChemCatChem 2009, 1, 89-93.

• Musa, M. M.; Fjeld-Ziegelmann, K. I.; Vieille, C.; Phillips, R. S. "Activity and selectivity of W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus in organic solvents and ionic liquids: mono- and biphasic media" Organic & Biomolecular Chemistry 2008, 6, 887-892.

•  Musa, M. M.; Fjeld-Ziegelmann, K. I.; Vieille, C.; Zeikus, G.; Phillips, R. S. "Xerogel-encapsulated W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus performs asymmetric reduction of hydrophobic ketones in organic solvents" Angew. Chem. Int. Ed. 2007, 46, 3091-3094.
  Featured in Synfacts 2007, 8, 889

• Fjeld-Ziegelmann, K. I.; Musa, M. M.; Phillips, R. S.; Zeikus, G.; Vieille, C. "A Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase mutant derivative highly active and stereoselective on phenylacetone and benzylacetone" Protein Engineering Design and Selection 2007, 20, 47-55.

• Musa, M. M.; Fjeld-Ziegelmann, K. I.; Vieille, C.; Zeikus, G.; Phillips, R. S. "Asymmetric reduction and oxidation of aromatic ketones and alcohols using W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus" Journal of Organic Chemistry 2007, 72, 30-34.

Book Chapters

• Musa, M. M.; Fjeld-Ziegelmann, K. I.; Vieille, C.; Zeikus, G.; Phillips, R. S. “Asymmetric reduction of phenyl-ring-containing ketones using xerogel-encapsulated W110A TeSADH secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus“ Practical Methods in Biocatalysis and Biotransformations Whittall, J.; Sutton, P., Eds, Wiley, 2010, pp 284-286.

Refereed Conference Publications with Proceeding

• Musa M. M. “Effect of substrate structure on enantioselectivity of Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase” 2nd Annual International Conference on Chemistry, Chemical Engineering and Chemical Process (CCECP 2014). doi: 10.5176/2301-3761_CCECP14.27

Conference Presentations

• Musa, M. M.;Karume, I.; Takahashi, M.; Hamdan, S. M. ““Stereoinversion ofStereoinversion of R-configured secondary alcohols using a single enzymatic approach” Biocatalysis Gordon Research Conference, July 08-13^th 2018.

• Musa, M. M.;Karume, I.; Takahashi, M.; Hamdan, S. M.. "Stereoinversion of"Stereoinversion of R-configured secondary alcohols using a single enzymatic approach” The 24^th Global Organic and Inorganic chemistry Conference, July 18-19^th 2018.

• Musa, M. M.;Karume, I.; Takahashi, M.; Hamdan, S. M. ““A Single Enzymatic Approach for Deracemization of Secondary Alcohols” The 13A Single Enzymatic Approach for Deracemization of Secondary Alcohols” The 13^th International Symposium on Biocatalysis and Biotransformations, July 09-13^th 2017.

• Musa, M. M.; Karume, I.; Takahashi, M.; Hamdan, S. M. “A Single Enzymatic Approach for Deracemization of Secondary Alcohols” The 5^th International Conference on Green Chemistry, July 24-26^th 2017.

• Karume, I.; Musa, M. M. “Compatibility of Thermoanaerobacter ethanolicus Secondary Alcohol Dehydrogenase and Candida Antarctica Lipase B: An Approach for Dual Enzymatic Dynamic Kinetic Resolution” The 10^th international conference & exhibition on chemistry in industry (ChemIndix), November 21^st- 23^rd 2016.

• Musa, M. M. “Deracemization of Secondary Alcohols Using a Single Alcohol Dehydrogenase” NYUAD International Chemistry Conference on Organic and Bioorganic Chemistry, Bahrain, February 16^th-18^th 2016..

• Alenaizan, A.; Al-Basheer, W.;Alenaizan, A.; Al-Basheer, W.; Musa, M. M. “Spectroscopic and theoretical investigation of solvent and temperature effects on optical activity of (R)-3-methylcyclohexanone dominant conformers ” The 2015 Combined Southwest and Southeast Regional Meetings of ACS, Memphis, TN, USA, 2015.

• Musa, M. M.; Karume, I.; Patel, J.; Takahashi, M.; Phillips, R. S.; Hamdan, S. M. “Turning alcohol dehydrogenases to recemases” 8th Singapore International Chemistry Conference, Singapore, 167, 2014.

• Karume, I.; El-Batta, A.; Khalil, A. B.; Musa, M. M.; Takahashi, M.; Hamdan, S. “Racemization of enantiopure alcohols by xerogel-immobilized alcohol dehydrogenase in organic solvents” 248^th ACS National Meeting and Exposition, San Francisco, CA, USA, ORGN182, 2014.

• Phillips, R. S.; Nealon, C.; Patel, J. M.; Kim, C. S.; Jang, Y., Musa, M. M. “Tuning the substrate specificity and stereospecificity of secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus” International Conference of Biocatalysis: Fundamentals and Applications, Moscow, Russia, 2013.

• Musa, M. M. “Racemization of enantiopure phenyl-ring-containing secondary alcohols using Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase” Gordon research conference in bioorganic chemistry, Andover, NH, USA, 2013.

• Musa, M. M. “Secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus in racemization of secondary alcohols” 23rd North American Catalysis Society Meeting, Louisville, Kentucky, USA, 2013.

• Musa, M. M.; Phillips, R. S. “Recent progress in asymmetric reduction of ketones using Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase”, 43rd Central Regional Meeting of the ACS, Dearborn, MI, USA, 2012.

• Musa, M. M.; Phillips, R. S. "Asymmetric synthesis of phenyl-ring-containing alcohols using Prelog and anti-Prelog Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase mutants", 11th Eurasia Conference on Chemical Sciences, Dead Sea, Jordan, 2010.

• Musa, M. M.; Gaffarogullari, E.; Veglia, G.; Distefano, M. D. “Approaches toward enzymatic dual site-specific labeling of peptides and proteins”, 238th ACS National Meeting, Washington, DC, USA, BIOL-151, 2009.

• Musa, M. M.; Distefano, M. D. “Bisubstrate analog inhibitors of protein farnesyltransferase”, 238^th ACS National Meeting, Washington, DC, USA, ORGN-120, 2009.

• Musa, M. M.; Phillips, R. S. “Asymmetric synthesis of optically active phenyl-ring-containing alcohols using sol-gel encapsulated W110A TeSADH”, 11^th Annual Green Chemistry and Engineering Conference, Washington DC, USA, Catalysis II-175, 2007.

• Musa, M. M.; Fjeld-Ziegelmann, K.; Vieille, C.; Zeikus, J. G.; Phillips, R. S.; “Asymmetric synthesis of optically active alcohols using free and sol-gel W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus”, UGA conference on Drug Discovery, University of Georgia, Athens, 2007.

• Musa, M. M.; Phillips, R. S. “Asymmetric reduction of ketones employing free and immobilized Thermoanaerobacter ethanolicus SADH”, Abstracts of Papers, 232^nd American Chemical Society National Meeting, San Francisco, CA, USA, ORGN-360, 2006.

• Musa, M. M..; Fjeld-Ziegelmann, K.; Zeikus, J. G.; Phillips, R. S.; “Biocatalytic asymmetric reduction of ketones by secondary alcohol dehydrogenase fromm Thermoanaerobacter ethanolicuss”, Biomedical and health sciences institute 44^thhannual retreat, University of Georgia, Athens,, 20055.