Resume

 

 

Home        Teaching        Resume        Publications

 

 

 

 

CURRICULUM VITAE - DR. A. A. ISAB

Name:                                                 Dr. Anvarhusein A. Isab

Date of Birth:                                    22nd April 1950.

Permanent Address:                         Motataiwad, Valsad (Gujarat)

                                                            India 396001.

Corresponding Address:                KFUPM # 1964 Dhahran 31261, Saudi Arabia                Tel:(009663) 860-5735  (Res.) 860-2645(Off)    FAX: 860-4277                                                               E-mail: aisab@kfupm.edu.sa

Joined KFUPM:                              Asst. Prof.: Sept. 1981 to Apr. 1984       

 Assoc.  Prof.:     May 1984 to Dec 1996

                                                          Professor           :     Jan 1997 to date

Academic Qualifications:

________________________________________________________________________

College/Univ.                      Exam.          Year                                  Subjects ________________________________________________________________________           

Science College,                   B.Sc.            1972                      Chem.(Special)                       

Valsad, India                                                                          English

Huddersfield Polytechnic                         1973                      Attended Eng. and Chem.     

Huddersfield, UK                                                                   Courses Sept.'73-Apr.'74

Birkbeck College                Ph.D.              1978                     Bio-Inorganic Chemistry  (Univ. of  London, UK)

________________________________________________________________­­____

Title of Thesis:           NMR Studies of Biologically Interesting Gold . Complexes (May 1978, Univ. of London)

 

 

Areas of Specialization:

1. Gold Biochemistry (Anti-arthritic Drugs)

The main research area emphasize the biological and inorganic chemistry of gold(I)-thiolate complexes which are active as antiarthritic agents. The ligand exchange reactions are being investigated by using NMR spectroscopy.

2. Thione/Thionine/Selenomethionine Complexes

      Imidazolidine-2 thione/Methionine/Selenomethionie and their derivatives are used as model ligands to synthesize various heavy metal complexes.

3. Captopril (A High Blood Pressure Drug)

      Captopril which has been used as a high blood pressure drug forms a crystalline complex with gold(I), which is first time in the history of gold(I)-thiolate complex is being crystalline. NMR is used to study the interaction of captopril with other heavy metal ions.

4. Impact of Cyanide ion on Smokers who are treated with Gold Drugs

      We are currently studying the reaction mechanism of cyanide ion with gold(I) drugs. Smokers on gold(I) therapy is found to have more toxic effects than nonsmokers. NMR is used to study the exchange reactions.

5. Red Blood Cells/ Serum Albumin

      The interaction of heavy metal ions with red blood cells as well as with serum albumin being investigated by NMR spectroscopy.

6. R3PAu13C15N and R3PAuS13C15N complexes

      Labeled R3PAuCN and R3PAuSCN new complexes are being synthesized which may have biological impact.

7. Selenocyanate and thiocyanate interactions

      Recently my Ph.D. student is working on the interaction of Selenocyanate and thiocyanate with Gold (I) drugs to understand the disproportionation reaction of the type CNSe-Au-thiols.

8. Solid state NMR studies Cd(II)-thione/selone complexes

      We have recently started synthesizing various Imidazolidine-2-thione and its derivatives complexes with Cd(II) and study them solution as well as in solid state in collaboration with Dr. M. I. M. Wazeer.

9. Ag13C15N complexes with thiones/selones

      Labeled Ag13C15N complexes are being synthesized with thiones/selones and study them with 109Ag NMR spectroscopy

10.  Novel Anticancer Gold (III) Complexes

        Recently we are involved in the collaboration with SAAD specialist hospital and Dammam Univ. Hospital to develop new gold (III) anti cancer drug. My students are involved in the synthesis, characterizations and anti-cancer measurement activities of several gold(III) and gold(I) complexes.

1.11Collaboration with the Physics Dept. on measurement of the elements

Comparison of Detection Sensitivities of Prompt Gamma ray Neutron Activation Analysis and Laser Induced Breakdown Spectroscopy  Techniques for Analysis of Toxic Elements Ag, Br, Cd, Cr, Cl, Gd, Hg, Ni and V in Liquid and Sold Samples

 

 

Teaching Experience

 

Following Chemistry and Environmental Chemistry Courses are taught by me here at KFUPM:

            CHEM 710 Ph.D. Thesis

            CHEM 610 MS Thesis

            CHEM 522 Organometallic Chemistry I

            CHEM 521 Advance Coordination Chemistry

            CHEM 412 Chem. Senior Project II         

            CHEM 411 and CHEM 471 Chem. Senior Project I                   

            CHEM 409 Chem. Seminar

            CHEM 331 Inorganic Chemistry

            CHEM 315 Introduction to Literature

            CHEM 306 Inorganic Chem. II (Lec./Lab)

            CHEM 161 Introduction to General Chemistry

            CHEM 102 General Chemistry II (SLF, LLF)

            CHEM 101 General Chemistry I (SLF, LLF)

Environmental Chemistry Courses

            EnvS   520 Advance Environmental Chemistry

            CHEM 463 Environmental Chemistry

            CHEM 111 Basics of Environmental Chemistry

 

Coordination of CHEM 102 course:

            CHEM 102: Coordination of course during 1983 to 1986 Preparing Lect/Lab Schedule, Reservation of Auditoriums, Coordinating all Major and Final exams for 800 to 1000 students, Prepare a final report for the Chairman.

 

Coordination of CHEM 101 course:

            CHEM 101: Coordination of course from summer 2009 to date

            The average number of students per semester is 700 (24 lecture sections).

            Responsibilities:

1.      To prepare the schedule from the assigned book (Burdge 2nd Ed, Publisher McGraw Hill) and distribute to the Faculty members to further distribute to his students

2.      To assign questions for the major exams and Final exam to the faculty members from the different chapters

3.      To prepare exams and print them as needed for the number of students

4.      To reserve auditoriums to conduct exams

5.      Analyze the computer graded exams and distribute the grades with the help of other faculty members.

Freshmen Labs Coordinator:  Fall ’89 to Spring ’02 (13 years of coordination of Freshmen CHEM 101 and CHEM 102 Labs).  I was involved in the development of the Freshmen experiments: 

Responsibilities: As a Freshman Lab Coordinator:

(a)    I was responsible for the CHEM 101/102 lab manuals to be printed by KFUPM press (total about 1000-1200 per year).

(b)   To supervise one chemist + two lab technicians.

(c)    To order chemicals and glassware for various experiments.

(d)   To substitute for any faculty members who is absent or cannot take any freshman labs (emergency).

During summer session, I helped in arranging labs assignments to different technicians so that labs run smoothly during summer.

Inorganic Division Supervisor: (Fall ’02 to date).  The curriculum of the Undergraduate programme was changed and currently involved in the development of the Inorganic experiments which can fit to the new syllabus of CHEM 331 course.

Responsibilities: As an Inorganic Division Supervisor, my job was

(a). To evaluate labs/update manual (order glassware/chemicals if necessary) for the Inorganic experiments.

(b).   To conduct MS/PhD entrance exams

(c).   Assign Inorganic courses among division members

(d).   To supervise one chemist

Laboratory Manuals CHEM 161

 

            CHEM 161: Revised CHEM 161 Lab manual while teaching the course. Printed 110 copies from 1987-1989 each year.                                                                                      

 CHEM 411/CHEM 412 Senior Projects:

            I have supervised (total Eighteen) senior research projects.

Awards :

      1. Holder of British Council Award Sept. '74 to June '78.

      2.   Alberta Heritage Foundation for Medical Research Fellowship (Edmonton, Alberta, Canada) Sept. '80 to Aug. '81.

     3. UWM NIEHS (Milwaukee WI USA) Marine and Fresh water Biomedical Core            Center Grant to carry out research on Lobster's Metallothionine June-Aug., 1989.

     4. The Best Research Award 1995-96.

     5. The Best Research Award 2001-02.

     6. The Best Research Award 2006-07.

     7.  The best Project award, Title: "Solid-state NMR study of Silver (I) complexes with             some sulphur containing biologically important ligands" 2006-07.

Editorial : 1.  Member of an Editorial Board of “Journal of Spectroscopy and Dynamics” Sept 2011 to Aug 2013.

      2.  Member of an Editorial Board of “Modern Chemotherapy” Aug 2013 to Aug 2014.

 

 

Professional Experience

      1.   April '74 to May 78, working as a Demonstrator for undergrad. students whilst working as a graduate student for Ph.D.

      2.   Aug.'77 to Feb.'78, with ICI (UK) Ltd. on development and analysis of formulated and bulk drugs by NMR and other physical techniques.

      3.   Postdoctoral Research Fellow at the Chem. Dept. with Prof. D. L. Rabenstein (Univ. of Alberta, Canada)  Nov. 78 to Aug. 81.

      4.   Sept. '81 to date: Teaching various Chemistry courses at the KFUPM

Membership:

      1.   Member of the American Chemical Society since 1979.

      2.   Member of the Saudi Arabian Intl. Chapters of the American Chemical Society since 1988.

Visiting Professor:

      1.   Visiting Prof. to the Chem. Dept., Univ. of Alberta during June '83 to Aug. '83 and June '84 to Aug. '84.

      2.   Visiting Prof. to the Chem. Dept., Univ. of Wisconsin, Milwaukee during June '89 to Aug. '89 and July '94 to Sept. '94.

Sabbatical Leave:

      1.   Worked with Prof. C. F. Shaw III at the Chem. Dept., Univ. of Wisconsin, Milwaukee, USA, during July 86 to Aug. 87. Published seven papers in the well-reputed journals like J. Am. Chem. Soc., Inorg. Chem., Biochem. Pharm. etc. Two more papers are under preparations.

      2.   Second Sabbatical Leave Aug. 97-Aug. 98. The title of the proposal, "Studies of Nucleotide and DNA Binding to Metallo-Anticancer Drugs". Host Scientist: Prof. L. G. Marzilli, Chemistry Department, Emory University, Atlanta, Georgia.

Collaborators:

            Smith Kline Beecham Pharm. (USA) into their Gold(I) based anti-arthritic drug programs (see publication nos. 17, 40, 43). Bristol Myers Squibb Pharm. Research Inst. for Medical Res.(USA) provides captopril (A high blood pressure drug) for my research. I collaborate my research with several faculty members here at KFUPM (see several of my publications). I also have international collaborators e.g. Prof. C. F. Shaw III (USA); Prof. P. J. Sadler (UK); Prof. J. D. Hoeschele (USA); Prof. G. Stocco (Italy) etc.

Consultants: Zahid H. Siddik, Ph. D. Professor of Medicine (Pharmacology), MD                               Anderson, Texas, USA.  Prof. Siddik is our consultant for one of our   projects entitled, "Synthesis, Characterization, Nephrotoxicity  and Cancer Cell        Resistance Studies of Novel Potential Anti Cancer Pt(II) Complexes"

           

            Dr. Ahmad Kasab, Asst. Prof. MD Anderson, Texas, USA. Dr. Kasab is our       consultant for our approved project, " Novel anticancer Gold(III) complexes:   Synthesis Chemical characterization, Drug sensitivity and      Kidney toxicity           studies"

Conference Organization as a Organizing Comm. Member: The 2nd Intl. Conf. and Exhibition on Laboratory Technology Labtech 2011, Ritz Carlton Hotel, 10-12 October, Doha, Qatar:

 

Research Projects at KFUPM:

Completed:

      1.   "Interaction of Metal Ions with Biologically Active Thiol Molecules Studies of NMR Spectroscopy".

            Duration: Apr.'82 to Mar.'84  (CY/METALION/54). Investigator: DR. A. A. ISAB

Granting Authority: KFUPM;  Budget: SR 355,000

      2.   "NMR Studies of Imidazolidine-2-thione and its derivatives"

            Duration: Jan. '85 to Dec.'88  (CY/NMRSTUDY/92).

            Investigator: DR. A. A. ISAB

Granting Authority: KFUPM;  Budget: SR 277,000

      3.   "Exchange Reactions of Bis(Thiomalato)-Gold(I) Complex with Thiols and other Biologically Important Ligands".

            Duration: Jan.'91 to Dec.'93  (CY/DRUG/124).

            Investigator: DR. A. A. ISAB

Granting Authority: KFUPM;  Budget: SR 295,000                   

      4.   "13C, 15N and 31P NMR Studies of the interaction of Cyanide Ion with Gold(I) Complexes"

            Duration: Oct.'95 to Dec '99 (CY/CYANIDE/175).

            Investigators: DR. A. A. ISAB (Principal Investigator) and DR. A. Al-ARFAJ (Co-Investigator)  (Number of papers generated: ten)

Granting Authority: KFUPM;  Budget: SR 310,000

5.      "13C, 15N, 77Se and 109Ag NMR Studies of M(I)-Imidazoloidine-2-thione and Imidazoloidine-2-selenone Complexes (Where M = Ag and Au)"

Investigators: DR. A. A. ISAB (Principal Investigator), DR. A. Al-ARFAJ (Co-Investigator)   and Dr. Dr. H. P. Perzanowski (Co-Investigator) 

            Duration: Sept.'00 to Mar '03 (CY/NMR-STUDIES/214).

            Investigators: DR. A. A. ISAB (Principal Investigator), DR. A. Al-Arfaj (Co-Investigator) and Dr. H. Perzanowski  (Co-Investigator).

Granting Authority: KFUPM;  Budget: SR 295,000

      6.   "13C, 31P and 77Se NMR Studies of the Redox and Exchange Reactions of Gold(I)   Drugs with Bis(alkylthio)selenides of Biological Thiols”

            Duration: Apr. '03 to Oct. '04 (SABIC/2003-08).

            Investigators: DR. A. A. Isab (Principal Investigator), DR. Waqar Ashraf (Co-Investigator).

Granting Authority: SABIC Industries;  Budget: SR 75,000

7        " Solid-state NMR study of Silver (I) complexes with some sulphur containing biologically important ligands”

Investigators: DR. A. A. ISAB (Principal Investigator), DR. M. I. M. Wazeer (Co-Investigator)

            Duration: June '04 to Nov '05 (SABIC/2004-01).

Granting Authority: SABIC Industries;  Budget: SR 75,000    

       8. "Multinuclear NMR Study of the Interactions of Some Sulfur containing

            Biologically Important Ligands with Cd2+ and Hg2+ Ions".

Investigators: DR. A. A. ISAB (Principal Investigator), DR. M. I. M. Wazeer (Co-Investigator)

            Duration: Sept '04 to Feb '07 (CY/NMR-STUDIES/277).

Granting Authority: KFUPM;  Budget: SR 325,000

9.      "Chelation of ethylenediammine and its derivatives with nd10 metal ions: Solution, Solid and X-ray structure studies”

Investigators: DR. A. A. ISAB (Principal Investigator), DR. M. I. M. Wazeer (Co-Investigator), Dr. M. Fettouhi (Co-Investigator)

            Duration: 1st Sept '06 to 29 Feb  '08 (SABIC/2006/08).

Granting Authority: SABIC Industries;  Budget: SR 75,000

10.  "Solid and solution NMR studies of 113Cd and 199Hg complexes with the constituents of DNA and Proteins"

Investigators: DR. A. A. ISAB (Principal Investigator), DR. M. I. M. Wazeer (Co-Investigator).

            Duration: 1st May '07 to 31st Oct.  '08 (SABIC SB070010).

Granting Authority: SABIC Industries; Budget: SR 75,000

11.  "Synthesis of Gold(III)-Diamines complexes and their Interactions with Biological Molecules Studies by solid and solution NMR"

Investigators: DR. A. A. ISAB (Principal Investigator), DR. M. I. M. Wazeer (Co-Investigator)

            Duration: Sept '07 to Feb '10 (CY/GOLD/374).

Granting Authority: KFUPM; Budget: SR 288,000

12."Redox and Ligand Exchange Reactions of Gold(III)-Cyanide and Gold(III)-        Selenocyanate             with various Biologically Important Ligands"

Investigators: DR. A. A. ISAB (Principal Investigator), DR. M. I. M. Wazeer (Co-Investigator)

            Duration: Sept '08 to Feb '11; 30 Months Project (IN080421).

13. "Novel Anticancer Gold (III) Complexes: Synthesis Chemical Characterization, Drug Sensitivity and Kidney Toxicity Studies"

Investigators: Dr. A. A. Isab(Principal Investigator), DR. M. I. M. Wazeer (Co-I), Dr. Saleh Altuwaijri (Co-I), Director, Clinical Research lab.Saad Specialist Hospital (SSH) Al-Khobar; Dr. Dalal Al-Tamimi (Co-I), Prof.& head pathology Department,
Dean University Studies of Women Campus, King Faisal University, Dammam, Dr A.Aziz M Alkhawajah, (Co-I) (Toxicologist), College of Medicine, King Faisal University, Al-Khobar .

 

Duration: Sept '09 to Aug '11

Funded by The 1st Five Year National Plan for Science and Technology, KACST

Granting Authority: KACST (NSTIP);  Budget: SR 1,323,200.00

 

      14."Design and Test of a 14 MeV Neutrons Based Prompt Gamma Neutron Activation Analysis Setup to Determine H, C, N and O Elements Concentration in Bulk samples With Low Atomic Number (Z)"

Investigators: Dr. A. A. Naqvi (Principal Investigator), DR. A. A. ISAB (Co-Investigator), et al.

Duration: May '09 to Nov '12 (IN09033).

Granting Authority: KFUPM;  Budget: SR1,048,520.00

15.  "NMR Studies of possible Interactions of Novel Potential Anticancer Gold(III) Complexes with Biologically Important Ligands"

Investigators: DR. A. A. ISAB (Principal Investigator), DR. M. I. M. Wazeer (Co-Investigator)

            Duration: Sept '10 to Feb '13 (30 Months Project) (IN100039).

Granting Authority: KFUPM;  Budget: SR 350,400.00

16. " Antitumor Activity and Nephrotoxicity Studies of some new Gold(III)                                     Complexes with diamines and dithiocarbamates mixed ligands."

Investigators: Dr. A. A. Isab(Principal Investigator), DR. M. I. M. Wazeer (Co-I), Dr. Saleh Altuwaijri (Co-I), Director, Clinical Research lab.Saad Specialist Hospital (SSH) Al-Khobar; Dr. Dalal Al-Tamimi (Co-I), Prof.& head pathology Department, Dean University Studies of Women Campus, King Faisal University, Dammam, Dr A.Aziz M Alkhawajah, (Co-I) (Toxicologist), College of Medicine, King Faisal University, Al-Khobar .

 

Duration: May '11 to April ‘13

Funded by the 3rd Five Year National Plan for Science and Technology, KACST

Granting Authority: KACST (NSTIP);  Budget: SR 1,226,200.00

 

In Progress:

 

17.       "Comparision of Detection Sensitivities of Prompt Gamma ray Neutron Activation Analysis and Laser Induced Breakdown Spectoscopy Techniques for Analysis of Toxic Elements Ag, Br, Cd, Cr, Cl, Gd, Hg, Ni and V in Liquid and Sold Samples"

Investigators: Dr. A. A. Naqvi (Principal Investigator), Dr. M. A. Gondal, DR. A. A. ISAB (Co-Investigator), et al.

Duration: Nov '11 to Nov '14   (RG1201-1 and RG1201-2).

Granting Authority: KFUPM;  Budget: SR 1,445,460.00

18.       " Antitumor activity of some new Gold(III) complexes of diphosphines with various alkyl diamine ligands to enhance clinical potential."

Investigators: Dr. A. A. Isab(Principal Investigator), DR. M. I. M. Wazeer (Co-I), Dr. Saleh Altuwaijri (Co-I), Director, Clinical Research lab.Saad Specialist Hospital (SSH) Al-Khobar; Dr. Dalal Al-Tamimi (Co-I), Prof.& head pathology Department, Dean University Studies of Women Campus, King Faisal University, Dammam, Dr A.Aziz M Alkhawajah, (Co-I) (Toxicologist), College of Medicine, King Faisal University, Al-Khobar .

 

Duration: Sept '12 to Aug ’14 (Completed)

Funded by the 3rd Five Year National Plan for Science and Technology, KACST

Granting Authority: KACST (NSTIP);  Budget: SR 1,450,200.00

19.       “Interaction of novel potential anticancer Gold (III) complexes of 1,2-diaminocyclohexane with nucleobases as well as thiol containing amino acids”

Investigators: DR. A. A. Isab (Principal Investigator), DR. M. I. M. Wazeer (Co-Investigator)

            Duration: May '13 to April '16 (36 Months Project) (IN121049).

Granting Authority: KFUPM;  Budget: SR 457,270.00

20.       "Nondestructive detection of petroleum contaminants in soil using Prompt Gamma Neutron Activation Analysis"

Investigators: F. Z. Khiari (Principal Investigator), Dr. A. A. Naqvi,  Dr. A. A. Isab, and Khateeb-u-Rehman

Duration: Sept '13 to Aug. '15  (NSTIP12-ENV2367-04).

Granting Authority: KACST (NSTIP);  Budget: SR 1,999,600.00

21.    “Synthesis and Characterization of some Platinum(II)-thione Complexes and their anti-      cancer activity against A549, HeLa and MCF7 cancer cell lines”

Investigator: Dr. A. A. Isab,

            Duration: 1st March '14 to 1st March '16 (24 Months Project) (IN131018).

22.       Anticancer activity of some new Gold(III) complexes with bipyridine and dithiocarbamates mixed ligands with potentially reduced nephrotoxicity” , project # 14-MED64-04

Investigators: Dr. A. A. Isab(Principal Investigator), DR. M. I. M. Wazeer (Co-I), Dr. Saleh Altuwaijri (Co-I), Director, Clinical Research lab.Saad Specialist Hospital (SSH) Al-Khobar; Dr. Dalal Al-Tamimi (Co-I), Prof.& head pathology Department, Dean University Studies of Women Campus, King Faisal University, Dammam, Dr A.Badar, (Co-I) (Toxicologist), College of Medicine, King Faisal University, Al-Khobar .

 

Duration: 1st March, 2015 to 28 Feb 2017

Funded by the 5th Five Year National Plan for Science and Technology, KACST

23.    “Synthesis and Characterization of some Platinum(II)-selone Complexes and their anti-      cancer activity against cancer cell lines”

Investigator: Dr. A. A. Isab and M. Altaf

            Duration: 1st May '15 to 1st May '18 (36 Months Project) (IN141029).

 

 

MS/Ph.D. Thesis:

Chairman of the Committee (MS degree)

1.       "15N and 13C NMR Studies of the Interaction of Cyanide ion with Gold Drugs", by Mr. Ibrahim H. Gazi  (MS, Completed June 1993). (Three papers have been published from his MS thesis; Publication # 52, 53 and #61).

      2.   "13C and 15N NMR Studies of Ligand Exchange Reactions of Auranofin and the Synthesis of   Gold(I) Complexes with Phosphine Sulfides and Phosphine Selenides", by Mr. Saeed Ahmad  (MS, Completed Nov 1997). (One paper have been published from his MS thesis; Publication # 72).

      3.   Synthesis and Characterization of Mononuclear Platinum(II) Complexes with Some Thione Ligands” by Mr. Ahmad Zain Abdalla ID # 201004480 (MS, Completed May 2013).

4.  "Synthesis and Characterization of some Thione containing Platinum (II) Complexes and their Anticancer Activity” by Mr. Mohammed Yagoub Ahmed Jomaa ID # 201204960 (MS, Completed 7th April 2015).).  

     5.  Interaction Studies of some Potential anticancer Gold(III) Complexes of 1,2-Diamine containing Ligands with Nucleobases and Amino acids” by Mr. M. Khalid H. Omaer ID # 201203760 (MS, Completed 12th April 2015).

 

Chairman of the Committee (Ph.D. degree)

1.       "13C, 15N and 31P NMR Studies of the Scrambling Reactions and the Redox Reactions of Some Gold(I) Complexes"  by Mr. M. N. Akhtar(ID # 920347) (Nine papers have been published). (PhD, Degree awarded in  Sept. 1996).

2.       "Synthesis, Characterization and NMR Studies of Some Gold (I) and Silver (I) Complexes with Cyanides, Thiones and Selenones” by Mr. A. Saeed ( ID # 950437)  (Thirteen papers have been published).  (PhD, Degree awarded in January, 2002).

3.       "Synthesis, Characterization and NMR Spectroscopic Studies of the Silver (I) Complexes with Heterocyclic Thiones and Tertiary Phosphine as Ligands" by Nora Othman Al-Zamil, Girls' College, Dammam, March 2007.

4.       Chelation of ethylenediammine and its derivatives nd10 metal ions: Solution and solid NMR and X-ray structure studies” Bassem A. M. Al-Maythalony (ID # 250475) (PhD, Degree awarded on 11th May, 2010).

5.       “Synthesis, characterization and anti-cancer activity of new gold(III) complexes with diamine and thione ligands”, Muhammad Monim-ul-Mehboob (ID #  7083992, PhD, Degree awarded on 2nd Oct, 2013)

6.       “Synthesis, Characterization and Evaluation of Anti-cancer activities of some Gold Complexes with Diamine, Phosphine and Dithiocarbamate as Ligands Said Salman Al-Jaroudi ID:198853740 (PhD, Degree awarded on 13th May, 2014)

7.       Synthesis, Characterization and Anti-Cancer Evaluation of New Mixed-Ligand Gold(I) Complexes with Dithiocarbamates and Phosphines” Adam Ahmed Abdallah Seliman ID: 201004460 (Full time student, Starting date 13th June 2013).

 

Member of the Committee (MS degree)

      1.   "Heterocyclic thione Complexes of Group IB Metals: Models of Gold Drugs", by M. L. Hossain. (June 1988).

2.       "Control of Corrosion in Steel using Polyelectrolytes Multilayers", by Abdallah A. Manda (ID # 220380) May 2007.

3.       "Flow Injection Analysis and Differential Electrolytic Potentiometry for Cyanide Determination" by Taufia Abda Saleh (ID # 220392) June, 2007.

4.       "Studying of various contaminants at Jubail port" by Yousef Ahmed Daboush (ID # 240372), (MS, Degree awarded on16th May, 2010).

5.       “Performance of Lanthanides-Halides Detectors in Prompt Gamma Analysis of Bulk Samples” by Mr. Mohammed Saleh Al-Anazi (ID # 200702450, Phys. Dept.) (MS, Degree awarded on 1st Jan., 2012).

Member of the Committee (Ph.D. degree)

      1. "NMR Study of Nitrogen Inversion and N-O Torsional Barriers and Anomeric Effect in Hydroxylamine Derivatives". (PhD, Degree awarded in Oct 1997). (Ph.D.; Mr. Hassan Azfar ID # 910596)

2.   Chain Transfer Agents: Characterizations and their use in Polymerization Reactions”. (PhD, Degree awarded in Jan. 2003). (PhD; Mr. Shafique Ahmad, ID No. 970329)

3.  "New group ten complexes based on ligands bearing nitronylnitroxide radicals.  Magnetic properties and catalytic activity in oxidation of alcohols" by Ahsan Mushir Shemsi; Student ID # 220296) (PhD, Degree awarded in May, 2008).

 4.  "Synthesis and characterization of new binuclear Cu(I) diimine and phosphine mixed ligand complexes: Catalytic applications in Carbon-Carbon bond formation reactions" by Atif Fazal Student ID # 200405400) (PhD Degree awarded in Jan 2010).

5.  "Microtitrimetry by Differential Electrolytic Potentiometry using Metallic Electrodes

and Nanomaterials Modified Metallic Electrodes" by Abdul Aziz N. Amro; Student ID # 200704730) (PhD, Degree awarded in May, 2012).

 

6. “Synthesis of some Linear and Cross-linked pH-Responsive Polycarbo-, Polyphospho- and Polysulfobetaines and their Applications in Water Treatment” by Othaman Al-Hamouz; Student ID # 200901870) (PhD, Degree awarded in March, 2013).

7. “Synthesis and Applications of some ionic Polymers as Antiscalants for Aqueous Two Phases Systems: by Kazi Izzat Wajih; Student ID # 199604950) (PhD Degree awarded in May, 2013).

8. “Cyclopolymerization Protocol in the Synthesis of a Novel Class of Linear and Cross-linked Polyzwitterions and their Apllications as Corrosion Inhibitors and Adsorbents” by Shamsuddin A. Haladu; Student ID # 20080250) (PhD Degree awarded in 10th  April, 2014).

9. “Structural and Electronic Properties, Vibrational Spectra and Catalytic Activity of New Rhodium- and Iridium-Based Complexes” by Saheed A. Popoola; Student ID # 201101870) (PhD Degree in progress).

          10. “Design, Synthesis and Evaluation of 1,3-Diaryl Pyrazoles as Inhibitors of

GGTase-I, a Target for Anti-cancer Drugs” by Muhammad Mansha

Student ID# 201204020 (PhD in progress).               

11. “Fabrication of Nanocomposite Electrode for Efficient Electrochemical conversion of 

    Carbon Dioxide to Value-Added Chemicals” by Ramadan Abd Elmonem Rabie Mohamed Geioushy, Student ID: 201206980 (PhD in progress).          

12. “Novel Graphene-modified Carbon Electrodes for Trace Eletroanalytical Determination of         L-tyrosine, Dopamine and Uric Acid Nadeem Baig, Student ID: 201207140 (PhD in

        progress).                                                                                                                        

13. “Study on electrochemically treated carbon electrodes for phenol,  α-naphthol and their selected derivatives detection” by M. Azeem A. Rana; Student ID # 201207120) (PhD Degree in progress).

14. “Development of sol-gel immobilized hybrid organic-inorganic silica based amine-functionalized coatings for capillary microextraction” by Shehzada M. S. Jillani; Student ID # 201207000) (PhD Degree in progress).

 

Member of the Committee (Ph.D. degree) as an external international examiner:

1.          “PHOSPHANE GOLD(I), SILVER(I) AND COPPER(I) DITHIOCARBAMATES: STUDIES ON ANTI-CANCER AND ANTI-BACTERIAL ACTIVITIES” by Nazzatush Shimar Binti Jamaludin, Institute of Graduate Studies, University of Malaya, 50603 Kuala Lumpur, Malaysia; Name of supervisor Prof. Edward Richard Tom Tiekink; 5th Sept 2015

2.          “SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF PHOSPHINEGOLD (I) THIOLATES” by Yeo Chien Ing, Institute of Graduate Studies, University of Malaya, 50603 Kuala Lumpur, Malaysia; Name of supervisor Prof. Edward Richard Tom Tiekink; 27th Sept. 2015

 

 

Work Reviewed

Reviewed two KACST Research proposals and also reviewed several                                 KFUPM Research proposal.

   Seminars  I have given several seminars in the Department and Internationally.

Some of my References Cited in Books/News Letter:

            1. My Red Blood Cells work was reviewed in the Chemical and Engineering News (Amer. Chem. Soc.), Aug. 31, 1981, p 38.

            2.  Book's References:

                  I.  "Advanced Inorganic Chemistry: A Comprehensive Text" by F. A. Cotton and G. Wilkinson;  Fourth Ed. p 977. (John Wiley and Sons, 1980).

                  II. "The Inorganic Chemistry of Biological Processes" by M. N. Hughes; Second Ed. pp 296-317. (John Wiley and Sons, 1976).

                  III."Transition Metal Complexes as Drugs and Chemotherapeutic Agents" by N. Farrell, Kluwer Academic Press, 1989, pp 243-254.

                  IV. "Metals and their Compounds in the Environment" by E. Merien, VCH Publishers, 1991, p 937.

                  V.     Bailliere's "Clinical Rheumatology: International Practice and Research" by P. M. Brooks, Vol. 4, No. 3, (Bailliere Tindall, 1990, pp 491-534).

            3.  Almost all "Review Articles" and most of the articles concerning Gold Drugs refer to my work.

            4.   Fackler et al (Texas A and M Univ. USA) in their paper of Inorg. Chem., 29, 4404-4407 (1990) referred some of our work as "Important Work" (our ref. Inorg. Chem., 28, 1321 (1989).

            5.   Elder et al (Univ. of Cincinnati, USA) in their paper of Inorg. Chem., 32, 2506-2517 (1993) referred some of our basic gold(I)-thiolate drug work as important work (our ref. J. C. S. Chem. Comm., 1051 (1976); J.C.S. Dalton Trans., 1657 (1981); 135 (1982).

Citations :  Average of over 30 citations per year by others in the international refereed journals.

 

Departmental Committees:

Name of the Committee                                                            Year              Status

---------------------------------------------------------------------------------------------------------

Safety Committee                                                                       1981/82          Member

Safety Committee                                                                       1982/83          Member

Safety Committee                                                                       1983/84          Member

Safety Committee                                                                       1984/85          Member

Curriculum Committee                                                                1985/86          Chairman

Sabbatical leave                                                                           1986/87            -

Curriculum Committee                                                                1987/88          Member

Curriculum Committee                                                                1988/89          Member

Staff Evaluation Committee                                                       1989/90          Chairman

Departmental budget comm.(ad-hoc)                                              "                Member

Set up Departmental Libr.(ad-hoc)                                             1989/90               -

Staff Evaluation Committee                                                       1990/91          Chairman

Research Committee                                                                        "                Member

Distinguished Teacher/Adviser(Ad-hoc)                                    1990/91          Member

Coordination of CAL lab                                                                "                     "

Departmental budget comm.(ad-hoc)                                             "                 Member

Staff Evaluation Committee                                                       1991/92          Member

Research Committee                                                                        "                Member

Departmental budget comm.(ad-hoc)                                               "               Member

Staff Evaluation Committee                                                       1992/93          Member

Departmental budget comm(ad-hoc)                                               "                Member

Departmental Freshman Lab Eval.  Comm(ad-hoc)                                         Chairman

Graduate Studies Committee                                                      1993/94          Member

Lab Development Committee                                                     1993/94          Member

Safety Committee                                                                       1994/95          Member

Lab Development Committee                                                     1994/95          Member

Distinguished Teacher/Adviser(Ad-hoc)                                    1994/95          Member

Graduate Studies Committee                                                      1995/96          Member

Lab Development Committee                                                     1995/96          Member

Safety Committee                                                                       1995/96          Member

Faculty Applications Eval. Comm.                                             1995/96         Member

Status of Lab Component of Freshman Chem. Course (Ad-hoc) 1995/96       Member

Faculty Applications Eval. Comm.                                             1996/97         Member

Lab Development Committee                                                     1996/97          Member

Information Comm.                                                                    1996/97         Member

Distinguished Teacher/Adviser(Ad-hoc)                                    1996/97          Member

Sabbatical Leave                                                                         1997/98         -

Lab Development Committee                                                     1998/99          Member

Information Comm.                                                                    1998/99         Member

Curriculum  Committee                                                               1998/99          Member

Lab Development Committee                                                     1999/00          Member

Safety Comm.                                                                             1999/00          Chairman

Seminar Org.  Committee                                                           1999/00          Member

Graduate Studies  Committee                                                     1999/00          Member

Chemistry Club                                                                           1999/00          Member

Faculty Promotion Regulation and Guidelines (Ad-Hoc)          1999/00          Member

Faculty Application Evaluation Committee                                2000/01          Chairman

Safety Comm.                                                                             2000/01          Member

Computer Utilization Comm.                                                      2000/01          Member

Distinguished Teacher/Adviser Award (Ad-hoc)                       2000/01          Chairman

Distinguished Teacher/Adviser Award (Ad-hoc) (College wide)2000/01        Member

To review CHEM 101/102 Lab Manuals (Ad-hoc)                    2000/01          Member

Faculty Application Evaluation Committee                                2001/02          Member

Lab Development Committee                                                     2001/02          Member

Graduate Studies Committee                                                      2001/02          Member

Faculty Application Evaluation Committee                                2002/03          Member

Lab Development Committee                                                     2002/03          Member

Curriculum Committee                                                                2002/03          Member

Safety Committee                                                                       2002/03          Member

To review CHEM 101/102 Lab Manuals (Ad-hoc)                    2002/03          Member

The Best Researcher Award (Ad-hoc) (College wide)               2002/03          Member

Teaching Committee                                                                   2003/04          Member

Research Committee                                                                   2003/04          Member

Planning & Advisory                                                                  2003/04          Member

Lab Development & Space Utilization Committee                    2003/04          Member

Eval. of undergrad. and graduate course files’ Comm.(Ad-hoc) 2003/04        Member

Safety Comm.                                                                             2004/05          Member

Environmental Science Graduate Prog (Ad-hoc) (College wide)2004/05        Member

Distinguished Teacher/Adviser Award (Ad-hoc)                       2004/05          Member

Text books for Industrial Chem. Programme (Ad-hoc)              2004/05          Chairman

Safety Comm.                                                                             2005/06          Chairman

Freshmen Comm.                                                                        2005/06          Member

Instruments’ supervisor Comm.                                                  2005/06          Member

Ad hoc Comm to evaluate special summer assignments             2005/06          Member

Steering Comm.                                                                          2005/06          Member

Promotion of Excellence in Research at KFUPM Comm.          2005/06          Member

(Task Group on Research Projects and Conferences) Ad-hoc Comm. Formed by the Rector.

Ad hoc Comm to nominate Chem Faculty Member for the

King Faisal Intl. Prize (Ad hoc)                                                  2005/06          Chairman

Distinguished Teacher/Adviser Award (Ad-hoc)                       2005/06          Member

Seminar & Social Activities                                                        2006/07          Member

Freshmen Teaching                                                                     2006/07          Member

Faculty & Staff Applications Evaluation                                    2006/07          Member

Freshmen Majors and Final Exams Comm.                                2006/07          Member

Research Advisory Comm. (Univ. wide) Chaired by the Rector2006/07         Member

Freshmen Teaching                                                                     2007/08          Member

Information and Publicity                                                           2007/08          Member

Research Advisory Comm. (Univ. wide) Chaired by the Rector2007/08         Member

Freshmen Teaching                                                                     2008/09          Member

Safety Comm.                                                                             2008/09          Member

Graduate Studies                                                                        2008/09          Member

Freshmen Teaching                                                                     2009/10          Chairman

Graduate Studies                                                                        2009/10          Member

Research Comm. (Univ.)                                                             2009/10          Member

Freshmen Teaching                                                                     2010/11          Chairman

Freshmen Teaching                                                                     2011/12          Chairman

The Best Researcher Award (Ad-hoc) (College wide)               2011/12          Member

3rd Scientific Conf. Comm. for Evaluating Grad Students         2011/12          Member

Freshmen Teaching                                                                     2012/13          Chairman

Undergraduate Research Prog (Task # 5) (Ad-hoc) (College wide) ”               Member

Inorg Div Prog (Task #2) (Ad-hoc) Chaired by Dr. Bassam El-Ali                  Member

Evaluating Chem. students’ papers for 4th Scientific Conf. Makkah                Member

Freshmen Teaching                                                                     2013/14          Chairman

Research Committee                                                                   2013/14          Member

Evaluating Chem. students’ papers for 5th Scientific Conf. Riyadh                 Member

Freshmen Teaching                                                                     2014/15          Chairman

Research Committee                                                                   2014/15          Member

Ad-hoc comm for reviewing learning outcomes, grading etc.    2014/15          Chairman

Scientific Research Council                                                        2014/15          Member

Curriculum Committee                                                                2015/16          Member

Scientific Research Council                                                        2015/16          Member

Freshmen Division                                                                      2015/16          Chairman