SCIENTIFIC   PUBLICATIONS  OF   DR.  A.  A. ISAB

1976-1980

1.              A. A. Isab and P. J. Sadler: "13C NMR Detection of Thiol Exchange on Gold(I): Significance in Chemotherapy"; J Chem. Soc. Chem. Comm.,1051-1052 (1976).  [Abstract]

2.             A. A. Isab and P. J. Sadler: "Reaction of Gold(III) Ions with Ribonuclease A and Methionine Derivatives in Aquous Solution"; Biochim. Biophys. Acta, 492, 322-30 (1977). [Abstract]

3.             A. A. Isab and D. L. Rabenstein: "The Incorporation 2H-Labelled Glycine into the Glutathione of Intact Human Erthyrocytes Studies by  1H Spin Echo Fourier Transform NMR"; Fed. Eur. Biochem. Soc. (FEBS) Letters, 106, 325-29 (1979). [Abstract]

4.             D. L. Rabenstein and A. A. Isab: "Water Elimination by T2 Relaxation in 1H Spin-Echo FT NMR Studies of Intact Human Erythrocyte and Protein Solution"; J. Mag. Res., 36, 281-86 (1979). [Abstract]

5.             D. L. Rabenstein, A. A. Isab and D. W. Brown: "Suppression of Hemoglobin Resonance in 1H NMR Spectra of Intact Erythrocytes," J. Mag. Res., 41, 361-365 (1980). [Abstract]

6.             D. L. Rabenstein and A. A. Isab: "The Complexation of Zinc Intact Human Erythrocytes Studied by 1H Spin-Echo NMR"; Fed. Eur. Biochem. Soc. (FEBS) Letters, 121, 61-64 (1980). [Abstract]

1981

7.             A. A. Isab and P. J. Sadler: "1H and 13C NMR Studies of Gold(I) Thiomalate ("Myocrisin") in Aqueous Solution: Dependence of the Solutions Structure on pH and Ionic Strength"; J. Chem. Soc. Dalton, 1657-63 (1981). [Abstract]

8.             D. L. Rabenstein, S. J. Backs and A. A. Isab: "NMR Studies of the Complexation of Trimethyllead by Glutathione in Aqueous Solution in Intact Human Erythrocytes," J. Amer. Chem. Soc.,  103, 2836-41 (1981). [Abstract]

1982

9.             D. L. Rabenstein, A. A. Isab and R. S. Reid: "A Proton NMR Study of the Binding of Methylmercury in Human Erythrocytes"; Biochim. Biophys. Acta, 696, 53-64 (1982). [Abstract]

10.           D. L. Rabenstein and A. A. Isab: "Conformational and Acid Base Equilibria of Captopril in Aqueous Solution"; Anal. Chem.,  54, 526-529 (1982). [Abstract]

11.           A. A. Isab and P. J. Sadler: "A Carbon-13 NMR Study of Thiol-Exchange Reactions of Gold(I)-Thiomalate ("Myocrisin") including Applications to Cysteine Derivatives"; J. Chem. Soc. Dalton, 135-141. (1982). [Abstract]

12.           D. L. Rabenstein, A. A. Isab and M. M. Shoukry: "NMR Studies of the Solution Chemistry of Metal Complexes.18. Complexation of Palladium(II) by Glycyl-L-histidine and Glycyl-L-histidylglycine"; Inorg. Chem., 21, 3234-36 (1982). [Abstract]

13.           D. L. Rabenstein and A. A. Isab: "Determination of the Intracellular pH of Intact Erythrocytes by 1H NMR Spectroscopy"; Analytical Biochemistry, 121, 423-31 (1982). [Abstract]

14.            D. L. Rabenstein and A. A. Isab: "A Proton NMR Study of the Interaction of Mercury with Intact Human Erythocytes"; Biochim. Biophys. Acta,  721, 374-384 (1982). [Abstract]

1983

15.           A. A. Isab: "A 1H NMR Study of the Reaction of Gold(III) with DL-Seleno-Methionine in Aqueous Solution"; Inorg. Chim. Acta, 80, L3-L4 (1983). [Abstract]

16.           D. L. Rabenstein, R. S. Reid and A. A. Isab: "An 1H NMR Study of the Effectiveness of various Thiols for Removal of Methylmercury from Hemolysed Erythrocytes"; J. Inorg. Biochemistry, 18, 241-251 (1983). [Abstract]

17.           D. T. Hill, B. M. Sutton, A. A. Isab, T. Razi, P. J. Sadler, J. M. Trooster and G. H. M. Calis, "Gold-197 Mossbaur Studies of some Gold(I)-Thiolates and their Phosphine Complexes including certain Antiarthritic Gold Drugs"; Inorg. Chem., 22, 2936-2942 (1983). [Abstract]

18.           G. Otiko, M. T. Razi, P. J. Sadler, A. A. Isab and D. L. Rabenstein: "A 1H NMR Study of the Interaction of Aurothiomalate ("Myocrisin") with Human Red Blood Cells in Vitro"; J. Inorg. Biochemistry, 19, 227-235 (1983). [Abstract]

19.           D. L. Rabenstein, A. A. Isab, W. Wadima and P. Mohankrishna: "A Proton NMR Study of the Interaction of Cadmium with Human Erythrocytes"Biochim. Biophys. Acta, 762, 531-541 (1983). [Abstract]

1984

20.           A. A. Isab: "A 1H NMR Study of the Binding of Hg2+ with DL-Seleno Methionine in Aqueous Solution"; Inorg. Chim. Acta, 91, L35-L37 (1984). [Abstract]

21.           M. S. Hussain and A. A. Isab: "Chloro(N-Ethyl-1,3-Imidazolidine -2-Thione) Gold(I): Spectroscopic Studies and X-Ray Structure"; Transition Metal Chem., 9, 398-401 (1984). [Abstract]

1985

22.           M. S. Hussain and A. A. Isab: "Synthesis, Spectroscopic Studies and X-ray Structure of Gold(I)-Complexes of N-Alkyl­Substituted Imidazolidine-2-Thione"; J. Coord. Chem., 14, 17-26 (1985). [Abstract]

23.           A. A. Isab and M. S. Hussain: "Synthesis, 13C and IR Spectroscopic Studies of Gold(I) Complexes of Imidazolidine-2-thione and its derivatives"; Polyhedron,  4, 1683-1686 (1985). [Abstract]

24.            A. A. Isab and A. P. Arnold: "Complexation of Methylmercury(II) by DL-Selenomethionine"; J. Coord. Chem., 14, 73-77 (1985). [Abstract]

25.           M. S. Hussain and A. A. Isab: "Bis(N-Propyl-1,3-Imidazolidine-2­ Thione) Gold(I) Chloride. Crystal and Molecular Structure"; Transition Metal Chem.,  10, 178-181 (1985). [Abstract]

26.           D. L. Rabenstein, S. A. Daignault, A. A. Isab, A. P. Arnold and M. M. Shoukary: "Nuclear Magnetic Resonance Studies of the Solution of Metal Complexes. 21. The Complexation of Zinc by Glycylhistidine and Alanylhistidine Peptides"; J. Amer. Chem. Soc., 107, 6435-6439 (1985). [Abstract]

27.           S. A. Daignault, A. P. Arnold, A. A. Isab and D. L. Rabenstein: "Nuclear Magnetic Resonance Studies of the Solution Chemistry of Metal Complexes. 22. The Complexation of Zinc by the Growth- Modulating Tripeptide Glycylhistidyllysine"; Inorg. Chem., 24, 3984-3988 (1985). [Abstract]

1986

28.           A. A. Isab: "Complexation of Gold(I)-Thiomalate 'Myocrisin' with 1,3-Diazinane-2-Thione in Aqueous Solution Followed by Carbon-13 NMR Spectroscopy"; J. Chem. Soc. Dalton Trans., 1049-1050 (1986). [Abstract]

29.           A. A. Isab and M. S. Hussain: "13C NMR and IR Studies of Copper(I) Complexes of the -NHCS Group in Five and Six-Membered Heterocyclic Rings"; Transition Metal Chem., 11, 298-301 (1986). [Abstract]

30.           A. A. Isab and M. S. Hussain: "Complexation of Imidazolidine-2-Thione and its Derivatives with Gold(I)-Cyanide"; J. Coord. Chem.,15, 125-130 (1986). [Abstract]

1987

31.           A. A. Isab: "Competition Between Gold(I)-Thiomalate 'Myocrisin' and Five and Six-Membered Heterocyclic Ligands"; Inorg. Chim. Acta, 135, 19-22 (1987). [Abstract]

32.           A. A. Isab: "A Reaction Between Captopril (A High Blood Pressure Drug) and Gold(I)-Thiomalate"; J. Inorg. Biochem.,  30, 69-75 (1987). [Abstract]

1988

33.           A. A. Isab, A. L. Hormann, M. T. Coffer and C. F. Shaw III: "Reversibly and Irriversibly Formed Products from the Reactions of Mercapalbumin (AlbSH) with Et3PAuCN and of AlbSAuPEt3 with HCN"; J. Amer. Chem. Soc., 110, 3278-3284 (1988). [Abstract]

34.           A. A. Isab: "13C NMR Chemical Shifts Comparision of 2-Aminovaleric Acid, L-Methionine and DL-Seleno-Methionine and their Interactions with Aurothiomalate in Aqueous Solution"; Inorg. Chim. Acta,153, 209-212 (1988). [Abstract]

35.            A. A. Isab, C. F. Shaw III and J. Locke: "GC-MS and17O NMR Tracer Studies of Et3PO Formation from Auranofin and H217O in the Presence of Bovine Serum Albumin: An in vitro Model for Auranofin Metabolism";  Inorg. Chem., 27, 3406-3409 (1988). [Abstract]

36.           A. A. Isab, C. F. Shaw III, J. D. Hoeschele and J. Locke: "Reactions of Trimethylphosphine Analogues of Auranofin with Bovine Serum Albumin"; Inorg. Chem. 27, 3588-3592 (1988). [Abstract]

1989

37.           A. A. Isab: "13C NMR Studies of the Interactions of HgII  with Methionine and Selenamethionine in the Acidic Aqueous Solution";Transition   Metal  Chem. 14, 235-236 (1989). [Abstract]

38.           A. A. Isab and  A. P. Arnold : " Exchange Reaction of Aurothiomalate with 3-Selenopropionate in Aqueous Solution";  J. Coord. Chem., 20, 95-97 (1989). [Abstract]

39.           A. A. Isab, A. L. Hormann, D. T. Hill, D. E. Griswold, M. J. DiMartino and C. F. Shaw III : "Bis(triethylphosphine)gold(I) Chloride: Ionization in Aqueous Solution, Reduction in vitro of the External and Internal Disulfide Bonds of Bovine Serum Albumin and an Anti-Arthritic Activity"; Inorg. Chem., 28, 1321-1326 (1989). [Abstract]

40.           A. A. Isab: "Synthesis and Spectroscopic Studies of Gold(I)-Thiocyanate with Imidazolidine-2-thione and its Derivatives"; Polyhedron, 23, 2823-2827 (1989). [Abstract]

1990

41.           A. A. Isab and C. F. Shaw III: "Synthesis of Thionato(Triethylphosphine) Gold(I) Complexes: Analogous to 'Auranofin' an Antiarthritic Drug"; J. Inorg. Biochem., 38, 95-100 (1990). [Abstract]

42.           C. F. Shaw III, A. A. Isab, M. T. Coffer and C. K. Mirbelli: "Glod(I) Efflux from Auranofin-Treated Red Blood Cells: Evidence for a Glutathione-Gold-Albumin Metabolite"; Biochem. Pharmacol.,  40, 1227-1234 (1990). [Abstract]

43.           A. A. Isab and H. P. Perzanowski: "1H, 13C and 199Hg NMR Studies of the Complexation of HgCl2  by Imidazolidine-2-thione and its derivatives", J. Coord. Chem.,21, 247-252 (1990). [Abstract]

1991

44.           A. A. Isab: "Estimated Formation Constants for Complexation of Methylmercury(II) by Captopril (A High Blood Pressure Drug): Evidence of Stronger Cis Isomer Binding to the Methylmercury(II) than Trans Isomer of the Drug", J. Chem. Soc. Dalton Trans., 449-452, (1991). [Abstract]

45.           A. A. Isab and A. A. Al-Arfaj: "Interaction of Palladium(II) with DL-Selenamethionine     in the Acidic Aqueous Solution", Transition Metal Chem., 16,  304-307 (1991). [Abstract]

1992

46.           A. A. Isab: "The 13C NMR Study of the Binding of Gold(I) Thiomalate with Ergothionine in Aqueous Solution", J. Inorg. Biochem.,  45,  261-267 (1992). [Abstract]

47.            Z. Zhu, M. Goodrich, A. A. Isab and C. F. Shaw III, : "Biphasic Reactions of DTNB with Lobster Cd6.- and Cd5Cu-Metallothionine-2 Which Have Two Type-B (M3S9) Clusters"; Inorg. Chem.. , 31, 1662-1667 (1992). [Abstract]

48.           A. A. Isab: "13C NMR Studies of the Disproportionation of Thioglucose gold(I)-13CN- Complex";  J. Inorg. Biochem.,  46,  145-151 (1992). [Abstract]

49.            A. A. Isab, H. P. Perzanowski and A. A. Al-Arfaj: "Bis and Multinuclear Gold(I) Complexes of 1,3-Diazepine-2-thione", Transition Metal Chem.,  17,  557-559 (1992). [Abstract]

50.           A. A. Isab, "Complexation of Silver nitrate with Imidazolidine-2-thione and its Derivatives", Transition Metal Chem.,  17,  374-376 (1992). [Abstract]

1993

51.            A. A. Isab, I. H. Gazi, M. I. M. Wazeer and H. P. Perzanowski: "15N NMR Studies of the Binding of C15N-  with  Gold(I) Drugs";  J. Inorg. Biochem.,  50, 299-304 (1993). [Abstract]

52.           A. A. Isab, I. Ghazi and A. A. Al-Arfaj:  "Complexation of Captopril (A High Blood Pressure Drug) with Gold(I) and its Exchange Reactions with Thiomalate and Cyanide",  J. Chem. Soc. Dalton Trans.,  841-845 (1993). [Abstract]

53.            A. A. Isab: "Studies on the Interaction of Gold(I) Thiomalate ('Myochrysine') with 2-Thiouracil in Aqueous Solution Followed by 13C NMR Spectroscopy"  Inorg. Chim. Acta,  207,  73-77 (1993). [Abstract]

54.           G. Stocco, F. Gattuso, A. A. Isab and C. F. Shaw III: "Synthesis and Characterization Complexes of Trialkyl- and Triarylphosphine Gold(I) with Thiolated Purines and Pyridimines: A Class of Bifunctional Compounds with Potential Antitumor  Activity"; Inorg. Chim. Acta,  209, 129-135 (1993). [Abstract]

1994

55.           A. A. Isab, A. A. Al-Arfaj, M. Arab and M. M. Hassan: "Complexation of Palladium Cyanide with Imidazolidine-2-thione and its Derivatives" Transition Metal Chem., 19,  87-90 (1994). [Abstract]

56.           C. F. Shaw III, A. A. Isab, J. D. Hoeschle, M. Starich, J. Locke, P. Schulteis and J. Xiao: "Oxidation of The Phosphine from the Auranofin Analogue, Tri iso propylphosphine (2,3,4,6-tetra-O-acetyl-1-thio-D-glucopyranosato-S-)gold(I) via a Protein bound Phosphonium Intermediate";  J. Amer. Chem. Soc.,  116,  2254-2260 (1994). [Abstract]

57.           A. A. Isab, A. A. Al-Arfaj and M. N. Akhtar: "The Redox Reaction of Gold(I)-Thiomalate in the presence of Selenourea",  J. Coord. Chem.,  33,  287-294 (1994). [Abstract]

58.           A. A. Isab:"Complexation of Seleno-cyteamine, Seleno-cysteaine and, Seleno-ethanoic acid with Gold(I) Thiomalate", Transition Metal Chem.,  19,  595-598 (1994). [Abstract]

1995

59.           A. A. Isab, M. N. Akhtar and A. R. Al-Arfaj: "13C NMR Studies of the Redox Reactions of Aurothiomalate and Bis Aurothiomalate with Selenocyanate in an Aqueous Solution",  J. Chem. Soc. Dalton Trans.,  1483-1488 (1995). [Abstract]

60.           M. N. Akhtar, I. H. Gazi, A. A. Isab, A. R. Al-Arfaj, M. I. M. Wazeer and M. S. Hussain:  "15N and 31P NMR Studies of Cyano (trialkyl/Triaryl) Phosphine Gold(I) Complexes",  J. Coord. Chem.,  36,  149-157 (1995). [Abstract]

1996

61.           A. R. Al-Arfaj, M. S. Hussain, A. A. Isab and M. N. Akhtar: "Bromo[tris(2 cyanoethyl) phosphine] Gold(I): [CEP-Au-Br]",  Acta Crystallo., C52, 550-553 (1996). [Abstract]

62.           A. A. Isab and H. P. Perzanowski: "1H, 13C and 199Hg NMR Studies of the -NHCS containing ligands with Mercuric halides", Polyhedron, 15, 2397-2401 (1996). [Abstract]

63.           M. S. Hussain, A. R. Al-Arfaj, M. N. Akhtar and A. A. Isab: "[{(CEP)2Au+}{Au(CN)2-}]: A Compound with Gold-Gold Bonds", Polyhedron, 15, 2781-2785 (1996).  [Abstract]

64.           A. A. Isab and M. N. Akhtar: "Comparative 13C  NMR Studies of Complexation of Imidazolidine-2- Selenone and its Analogous Thione to Gold(I) Thiomalate", J. Coord. Chem., 39, 21-31 (1996). [Abstract]

65.           M. N. Akhtar, A. A. Isab and M. I. M. Wazeer: "Characterization of Polymeric Gold(I) Captopril Complex using Viscosity and Various Spectroscopic Techniques",  J. Inorg. Biochem., 64, 37-53 (1996). [Abstract]

66.           M. N. Akhtar, A. A. Isab, M. S. Hussain and A. R. Al-Arfaj, "Synthesis of thionato(trimethylphosphine) Gold(I) complexes", Transition Met. Chem., 21, 553-555 (1996). [Abstract]

1997

67.           M. N. Akhtar, A. A. Isab, M. S. Hussain and A. R. Al-Arfaj, "Synthesis of thiocyanato(trialkyl/triaryl)phosphine Gold(I) Complexes", Polyhedron, 16, 125-132 (1997). [Abstract]

68.           M. N. Akhtar, A. A. Isab, and A. R. Al-Arfaj, "13C and 15N NMR Studies of the Interaction of Gold(I) Captopril with Selenocyanate, Selenourea and Thiourea in Aqueous Solution", J. Inorg. Biochem., 66, 197-205 (1997). [Abstract]

69.           A. R. Al-Arfaj, H. J. Reibenspies, M. S. Hussain,  M. N. Akhtar and A. A. Isab: "Crystal Structure of Cyano-Tri(cyclohexyl)phosphino Gold(I)",  Acta Crystallo., C53, 1553-1555 (1997). [Abstract]

1998

70.           A. R. Al-Arfaj, M. S. Hussain, H. J. Reibenspies and A. A. Isab: "Crystal Structure of Dichloro-Bis(Imidazolidine-2-Thione) Cadmium",  Acta Crystallo., C54, 51-53 (1998). [Abstract]

71.           A. R. Al-Arfaj, A. A. Saeed, M. N. Akhtar, and A. A. Isab: "Simultaneous Replacements of Triethyl Phosphine and Tetraacetyl Thioglucose Ligands from Auranofin (an Anti-arthritic drug) with Selenocyanate:13C and 31P NMR Studies",  J. Coord. Chem., 43, 257-272 (1998). [Abstract]

72.                 A. A. Isab and M. S. Hussain: "1H and 13C  NMR Studies of the Complexation of Zn2+ to the Trans Isomer of Captopril: (A High Blood Pressure Drug)", Can. J. Anal. Sci. Spetroscopy, 42, 102-106 (1998).  [Abstract]

73.           A. J. Canumalla, S. Sahraa, A. A. Isab, C. F. Shaw III, E. Gleichmann, L. Dunemann and M. Turfed : "Equilibrium Binding Constants and Facile dissociation of Novel Serum Albumin-Dicyanoaurate(I) Complexes",  J. Biol. Inorg. Chem., 3, 9-17 (1998). [Abstract]

74.           A. R. Al-Arfaj, H. J. Reibenspies, M. S. Hussain and A. A. Isab: "R3PAuCN Complexes: [{Ph2(cyclohexyl)P}AuCN] and [{m-Tolyl)3P}AuCN]",  Acta Crystallo., C54, 716-719 (1998). [Abstract]

75.           M. S. Hussain, A. R. Al-Arfaj, A. A. Isab and H. J. Reibenspies: "Crystal Structure of Cyanotri(isopropyl)phosphinegold(I), [(C3H7)3PAuCN] ", Z. Kristallogr., NCS, 213,  517-518 (1998). [Abstract]

76.                 A. A. Isab and L. G. Marzilli : "Supermacrochelate Complexes Containing an Artificial Nucleic Acid Backbone and Derived from Excellent Ligands Formed by Treating Platinum Anticancer Agents with Nucleotide Triphosphate ", Inorg. Chem., 37, 6558-6559 (1998). [Abstract]

1999

77.                 A. A. Isab, M. S. Hussain, M. N. Akhtar, M. I. M. Wazeer and A. R. Al-Arfaj, "13C, 15N and 31P NMR Studies of the Disproportination of Cyanogold(I) Complexes: [R3PAu13C15N]", Polyhedron, 18,  1401-1409 (1999). [Abstract]

2000

78.           M. N. Akhtar, A. A. Isab, and A. Hassan, "Thermal Decomposition of Trialkyl/Arylphosphine Gold(I) Cyanide Complexes", J. Thermal Anal. And Calorimetry, 61, 119-125 ( 2000). [Abstract]

79.                 S. Ahmad, A. A. Isab, M. N. Akhtar,  M. S. Hussain,  and A. R. Al-Arfaj, "Gold(I) Complexation with Trialkyl/Triaryl Phosphine Selenide Complexes", J. Coord. Chem, 51, 225-234 ( 2000). [Abstract]

80.           M. S. Hussain and A. A. Isab “ Spectroscopic Study of Phosphine Selenide Complexes of Au(I)  and X-ray structure of [(Cyclohexyl)3PseAuBr]”,   J. Chem.Crystallo., 30, 731-735 ( 2000). [Abstract]

2001

81.           A. J. Canumalla, N. Al-Zamil, M. Philips, A. A. Isab and C. F. Shaw III: "Redox and Ligand Exchange Reactions of Potential Gold(I) and Gold(III)-Cyanide Metabolites under Biomimetic Conditions",  J. Inorg. Biochem. , 85,  67-76 (2001). [Abstract]

82.           M. S. Hussain and A. A. Isab “ Crystal Structure of bromotri(phenyl)phospineselenidegold(I), (C6H5)3PSeAuBr”,   Z. Kristallogr., NCS, 216, 479-480 (2001). [Abstract]

83.                 S. Ahmad and A. A. Isab “ Synthesis of Cyano(ergothionine)gold (I) Complexes and its Disproportionation in Solution”, Inorg. Chem. Comm.,  4, 362-364 (2001). [Abstract]

84.           M. S. Hussain, A. A. Isab, A. Saeed and A. R. Al-Arfaj “Crystal Structure of bromotri(phenyl)phospinesulfidegold(I), (C6H5)3PSAuBr”,   Z. Kristallogr., NCS, 216, 629-630 (2001). [Abstract]

2002

85.           S. Ahmad and A. A. Isab, "13C, 31P and 15N NMR Studies of the Ligand Exchange Reactions of Auranofin and  Chloro(Triethylphosphine)Gold(I) with Thiourea” J.  Inorg. Biochem.,  88, 44-52 (2002). [Abstract]

86.           A. A. Isab and S. Ahmad, "Comparative 13C and 31P NMR Studies of the Ligand Exchange Reactions of Auranofin  with Ergothionine, Imidazolidine-2-Thione and Diazinane-2-Thione” J. Inorg. Biochem., 88, 53-60 (2002). [Abstract]

87.                 S. Ahmad and A. A. Isab: "13C NMR Studies of the Interaction of Gold(I) Thiomalate with 6-Mercaptopurine and its Derivatives” J. Coord. Chem., 55, 189-203 (2002). [Abstract]

88.                 S. Ahmad, A. A. Isab, H. P. Perzanowski, M. S. Hussain and M. N. Akhtar “ Gold(I) Complexes with Tertiary Phosphinesulfide Ligands”, Transition Metal Chem., 27, 177-183 (2002). [Abstract]

89.                 S. Ahmad and A. A. Isab: “Silver(I) Complexes of Selenourea (13C and 15N Labeled); Characterization by  13C, 15N and  107Ag NMR”, Inorg. Chem. Comm., 5, 355-357 (2002). [Abstract]

90.                 A. A. Isab, S. Ahmad and M. Arab “Synthesis of silver(I) complexes of thiones and their characterization by 13C, 15N and 107Ag NMR Spectroscopy” Polyhedron, 21, 1267-1271 (2002). [Abstract]

91.                  S. Ahmad, A. A. Isab, A. R. Al-Arfaj and A. P. Arnold “Synthesis of cyano(selenone)gold(I) complexes and    investigation of their scrambling reactions using 13C and 15N NMR spectroscopy” Polyhedron, 21, 2099-2105 (2002). [Abstract]

92.              S. Ahmad, A. A. Isab and W. Ashraf “Multinuclear NMR (1H, 13C, 15N and 107Ag) studies of the silver cyanide complexes of thiourea and substituted thioureas” Inorg. Chem. Comm., 5,  816-819 (2002). [Abstract]

93.              S. Ahmad, A. A. Isab and H. P. Perzanowski, “ Silver(I) Complexes of Thiourea”, Transition Metal Chem., 27, 782-85 (2002). [Abstract]

94.           S. Ahmad, A. A. Isab and H. P. Perzanowski “Ligand Scrambling Reactions of Cyano(thione)gold(I) Complexes and Determination of their Equilibrium Constants” Canadian J. Chem., 80, 1279-84 (2002). [Abstract]

95.          S. Ahmad, A. A. Isab and M. I. M. Wazeer, "13C NMR Studies of the Redox and Exchange Reactions of Gold(I) Thiomalate with Diselenides”  Inorg. Reaction Mechanisms.,  4, 95-102 (2002). [Abstract]

96.          A. A. Isab and S. Ahmad “13C and 15N NMR Studies of the Ligand Scrambling Reactions of some Cyano(selenone)gold(I) Gomplexes in Dimethyl sulfoxide” Can. J. Anal. Sci. Spectroscopy, 47, 1-5 (2002). [Abstract]

2003

97.                 A. A. Isab,  S. Ahmad, A. R. Al-Arfaj and M. N. Akhtar “13C AND 15N NMR Studies of the  Interaction of Gold(I) Thiolates with Thiourea (13C AND 15N Labeled)” J. Coord. Chem., 56, 95-101 (2003). [Abstract]

98.          S. Ahmad and A. A. Isab, "Mixed Ligand Gold(I) Complexes with Phosphines and Selenourea”   Transition Metal Chem.,  28, 540-543 (2003). [Abstract]

99.           A. A. Isab, M. Fettouhi, S. Ahmad and L. Ouahab, “Mixed ligand gold (I) complexes of phosphines and thiourea and X-ray structure of (Thiourea-κS)(tricyclohexylphosphine)gold(I)chloride” Polyhedron, 22, 1349-54 (2003). [Abstract]

100.         S. Ahmad, A. A. Isab, and A. P. Arnold “Synthesis and Spectroscopic Characterization of Silver(I) Complexes of Selenones” J. Coord. Chem., 56, 539-544 (2003). [Abstract]

101.              M. I. M. Wazeer, A. A. Isab, and H. P. Perzanowski “Solid-state NMR study of 1,3 –imidazolidine-2-selenone and some related compounds” Magn. Res. Spectroscopy, 41, 1026-29 (2003). [Abstract]

102.              S. Ahmad, A. A. Isab, and S. Ahmad, “1H, 13C, 15N NMR and IR Spectroscopic Studies of Rh(II) Complex of   (13C, 15N label) Thiourea” J. Coord. Chem., 56, 1587-95 (2003). [Abstract]

2004

103.         M. I. M. Wazeer, A. A. Isab, and A. El-Rayyes “Solid-state NMR study of 1,3 –imidazolidine-2-thione, 1,3-imidazolidine–2-selenone and some of their N-substituted derivatives” Spectroscopy, 18, 113-119 (2004). [Abstract]

104.         M. Fettouhi, M. I. M. Wazeer, S. Ahmad  and A. A. Isab* “X-ray structure and  77Se, 31P and 13C  MAS NMR of the dinuclear complex 1,2-bis(selenourea)-1\κSe,2\κSe-1,2-bis(trimethylphosphine)digold(I) chloride” Polyhedron, 23, 1-4 (2004). [Abstract]

105.              W. Ashraf, S. Ahmad and A. A. Isab, "Silver cyanide complexes of heterocyclic thiones”  Transition Metal Chem.,  29, 400-404 (2004). [Abstract]

106.      W. Ashraf and A. A. Isab, “31P NMR Studies of the Redox Reactions of Bis Trialkylphosphine Gold (I)  Bromide (where alkyl = methyl and ethyl) with Disulphide and Diselenide Ligands” J. Coord. Chem., 57, 337-346 (2004). [Abstract]

107.         M. Fettouhi*, A. A. Isab and M. I. M. Wazeer “Crystal structure of bis (3,4,5-tetrahydropyrimidine-2(1H)-thionegold(I) chloride, [Au(C4H8N2S)2]Cl”  Z. Kristallogr., NCS, 219, 391-392  (2004). [Abstract]

108.      A. A. Isab, S. Ahmad and A. P. Arnold “Gold(I) complexes with selenone and triphenylphosphine as ligands” Transition Metal Chem., 29, 870-873 (2004). [Abstract]

109.        A. A. Isab, C. F. Shaw III, A. Munoz and J. D. Hoeschele, "Exchange Reactions between Albumin-Au(I)-PEt3 Complex and Me3PAuCl or iPr3PAuCl: 31P NMR Spectroscopic Studies”  Inorg. Reaction Mechanisms.,  5, 109-116 (2004). [Abstract]

2005

110.       A. A. Isab and W. Ashraf, “Oxidation of Diselenide bond with sodiumtetracloroaurate(III): Significance in Chemotherapy”, Inorg. Chem. Comm., 8, 358-360 (2005). [Abstract]

111.       M. I. M. Wazeer, A. A. Isab, and S. Ahmad, “Solution and Solid State NMR Studies of some Selenium Analogues of Auranofin (an Anti-Arthritic Gold Drug)” J. Coord. Chem., 58, 391-398 (2005). [Abstract]

112.     A. A. Isab and M. I. M. Wazeer, “Complexations of Zinc(II),  Cadmium(II) and Mercury(II)  with Thiourea and Selenourea: 1H, 13C, 15N, 77Se and 113Cd Solution and Solid state NMR studies”,  J. Coord. Chem ., 58, 529-537 (2005). [Abstract]

113.       A. A. Isab, S. Ahmad and W. Ashraf, “13C NMR studies of the binding of 1,3-diazinane-2-selenone and 1,3-diazipine-2-selenone to gold(I) drugs” Transition Metal Chem.,  30, 389-392 (2005). [Abstract]

114.       M. I. M. Wazeer and A. A. Isab, “Solution and Solid-State NMR Studies of Some Cadmium-Selenone Complexes” Spectro.Chim .Acta (A), 62, 880-885 (2005). [Abstract]

115.       A. D. Al-Amri, M. Fettouhi, M. I. M. Wazeer and A. A. Isab, “Synthesis, X-ray structure and 199Hg, 77Se CP MAS NMR studies on the first tris(imidazolidine-2-selone) mercury complex: {Chloro-tris[N-methyl-2(3H)-imidazolidine-2-selone]mercury(II)}chloride” , Inorg. Chem. Comm.,  8, 1109-1112 (2005). [Abstract]

116.         A. A. Isab and M. I. M. Wazeer,  “A 13C NMR study of the interactions of Ag13CN and Ag(CN)2- with thiomalic acid, L-Methionine and DL-Seleno-methionine.” Spectroscopy, 19, 275-281(2005). [Abstract]

2006

117.       A. A. Isab and M. I. M. Wazeer, “Solid and Solution 13C NMR Studies of the Complexation of Ag+ to the Trans Isomer of Captopril:  Biological Activities of this High Blood Pressure Drug along with its Ag+ Complex” Spectro.Chim .Acta (A), 65, 191-195 (2006). [Abstract]

118.       M. I. M. Wazeer, A. A. Isab and S. Ahmed  “Solution and Solid-State NMR Studies of Thiourea, Selenourea, N,N-Dimethyl selenourea and their Ag(I) Complexes" Can. J. Anal. Spectroscopy, 51, 43-48 (2006).

119.       A. A. Isab, and S. Ahmad, "Complexation of gold(I) trimethylphosphine with selenone containing ligands” Transition Metal Chem 31, 500-503 (2006). [Abstract]

120.         S. Ahmad, A. A. Isab, S. Ali and A. R. Al-Arfaj, "Perspectives in bioinorganic chemistry of some metal based therapeutic agents", Polyhedron, 25, 1633-1655 (2006). [Abstract]

121.              A. A. Isab,  M. I. M. Wazeer, M. Fettouhi, S. Ahmad and W. Ashraf, " Synthesis and Characterization of Mercury(II) Complexes of Selones: X-ray Structure, CP MAS and Solution NMR Studies" Polyhedron,, 25, 2629-2636 (2006). [Abstract]

122.       M. Fettouh, M. I. M. Wazeer and A. A. Isab, " Crystal structure of dibromo-bis(1,3-imidazolidine-2-thione-S)zinc(II), ZnBr2(C3H6N2S)2"  Z. Kristallogr., NCS, 221, 221-222 (2006). [Abstract]

123.       A. A. Isab, and S. Ahmad, " Applications of NMR spectroscopy in understanding the gold biochemistry” Spectroscopy, 4,109-123 (2006). [Abstract]

124.         S. Ahmad, A. A. Isab and S. Ali, " Structural and Mechanistic Aspects of some Metal Based TherapeuticAgents", Transition Metal Chem. 31, 1003-1016 (2006). [Abstract]

2007

125.         M. Fettouhi, M. I. M. Wazeer and A. A. Isab, "New Zinc halide complexes with Imidazolidine-2-thione and its derivatives: X-ray structures, Solid State, Solution NMR and Antimicrobial Activity Studies" J. Coord. Chem.,60, 369-377 (2007). [Abstract]

126.      A. A. Isab and M. I. M. Wazeer "Synthesis and Characterization of Thiolate-Ag(I) Complexes by Solid State and Solution NMR   and their Antimicrobial Activity" Spectro.Chim .Acta (A),  66, 364-370 (2007). [Abstract]

127.      M. I. M. Wazeer, A. A. Isab and M. Fettouhi, " New Cadmium chloride complexes with Imidazolidine-2-thione and its derivatives: X-ray structures, Solid State and Solution NMR and Antimicrobial Activity Studies" Polyhedron, 26,

             1725-1730 (2007). [Abstract]

128.  N. O. Al-Zamil, K. A.  Al-Sadhan, A. A. Isab, M. I. M. Wazeer and A. A. Al-Arfaj, "Silver(I) complexes of Imidazolidine-2-thione and triphenylphosphines: Solid-State, Solution NMR and Antimicrobial Activity Studies" Spectroscopy, 21, 61-67 (2007). [Abstract]

129.         A. A. Isab,  M. I. M. Wazeer, M. Fettouhi, B. A. Al-Maythalony, A. R. Al-Arfaj and N. O. Al-Zamil "Solid state and solution NMR, X-ray and antimicrobial studies of 1:1 and 2:1 complexes of silver (I) cyanide with alkanediamine ligands"                Inorg. Chim. Acta., 360, 3719-3726 (2007). [Abstract]

130.         M. I. M. Wazeer and A. A. Isab, "Solid State and Solution NMR Studies of Some New Complexes of Mercury Selenocyanate with Imidazolidine-2-thione and its derivatives" J. Coord. Chem., 60, 2649-2657 (2007). [Abstract]

131.         M. I. M. Wazeer and A. A. Isab, " Complexations of Hg(CN)2 with Imidazolidine-2-thione and its   derivatives: Solid State, Solution NMR and Antimicrobial Activity Studies" Spectro. Chim. Acta (A), 68, 1207-1212 (2007).

                [Abstract]

2008

132.         M. Fettouhi,, M. I. M. Wazeer and A. A. Isab, "A novel polymeric Cd[SSe2N2] central core five-coordinate    complex:   Synthesis, X-ray structure and 113Cd, 77Se CP MAS NMR characterization of catena(bis(µ2-        selenocyanato-N,Se)-(N,N'-               dimethylimidazolidine-2-thione-S)-cadmium(II))" Inorg Chem. Comm., 11, 252-255 (2008). [Abstract]

133.         M. Hanif, A. Saddiqa, S. Hasnain, S. Ahmad, G. Rabbani, and A. A. Isab, " Preparation, Spectral  Characterization and Antibacterial Studies of Silver(I) Complexes of Mercaptopyridine and Thiomalate"   Spectroscopy, (Accepted for the publication  2008). [Abstract]

 

 

 

 

               


Papers/Posters Presented to Conferences,

Professional meetings, Seminars, Symposia etc :

 

 

1.             A. A. Isab and P. J. Sadler, "Molecular State of Some Gold(I) Thiol Drugs in Aqueous Solution as seen by 1H and 13C NMR Spectroscopy", paper presented at the Autum Meeting of the Chemical Society and Sheffield University, England, Sept. 1976.

 

2.             D. L. Rabenstein, A. A. Isab and T. T. Nakashima,  "1H NMR Studies of small Molecules in Intact Red Blood Cells," 21st Experimental NMR Conference,  Florida, March, 1980.

 

3.             D. L. Rabenstein and A. A. Isab, "Determination of the Intracellular pH of Intact Erythrocytes by 1H NMR Spectroscopy," 63rd Canadian Chemical Conference & Exhibition, Ottawa, Canada, June 8-11, 1980.

 

4.              D. L. Rabenstein and A. A. Isab, "1H NMR Studies of Complexation of Heavy Metals in Intact Red Blood Cells," 2nd Chemical Congress of the North American Continent, Las Vegas, U. S. A. August, 1980.

 

5.             A. A. Isab, R. S. Reid and D. L. Rabenstein, "An 1H NMR Study of the Complexation of Methylmercury in Intact Red Blood Cells," 64th Canadian Chemical Conference & Exhibition, Halifax, Canada, May 31 - June 3, 1981.

 

6.             D. L. Rabenstein, A. A. Isab and R. S. Reid, "Complexation of CH3Hg(II) in Intact Human Erythrocytes Studies by 1H NMR Spectroscopy ," 28th Congress of the International Union of Pure and Applied Chemistry, Vancouver, Canada, Aug. 16-21, 1981.

 

7.             A. A. Isab, D. L. Rabenstein and R. S. Reid, "Complexation of Heavy Metal Ions with Human Red Blood Cells by 1H NMR Spectroscopy" The First Conference on NMR Spectroscopy, Mosul, Iraq, Oct. 1982.

 

8.             D. L. Rabenstein, A. A. Isab R. S. Reid, W. Kadima and Manmohankrishna, "The Binding of Zinc, Cadmium, Mercury & Methylmercury in Human Erythrocytes," 66th Canadian Chemical Conference, 5-8 June, 1983, Calgary, Alberta, Canada.

 

9.             A. A. Isab, "1H NMR Studies of the Interaction of Heavy Metal Ions such as Gold(I), Gold(III) and Mercury(II) with DL-Selenomethionine in Aqueous Solutions", Canadian-American Chemical Congress (67th Canadian Chemical Conference), 3-6 June, 1984, Montreal, Quebec, Canada.

 

10.           A. A. Isab and C. F. Shaw III, "Bioinorganic Chemistry of Gold Drugs", Third National Meeting of Chemists, 12-14 March, 1989, KFUPM, Dhahran, Saudi Arabia. Abstract No. 53.

 

11.           C. F. Shaw III, A. A. Isab, M. T. Coffer and J. locke, "Albumin and Thiol Stimulated Oxidation of Phosphines from the Metallodrug Auranofin and Analogous",  Fourth International Conference on Bioinorganic Chemistry, 23-28 July, 1989, Cmbridge, MA  U.S.A. Abstract No. A026 in the J. Inorg. Biochem., Vol. 36, 1989.

 

12.           C. F. Shaw III, M. Starich, J. Locke and A. A. Isab, "The Inorganic Biochemistry of Gold-Based Anti-Arthritic Drugs", The American Chemical Society, Southern California Section: The International Chemical Congress of Pacific Basin Conference on Chemistry and Spectroscoy, 18-21 October, 1989, Pasadena,  California,  U.S.A

.

13.           C. F. Shaw III, M. Coffer and A. A. Isab, "Albumin-Gold-Glutathione is a Probable Auranofin Metabolite", The American Chemical Society, Southern California Section:  The International Chemical Congress of Pacific Basin Conference on Chemistry and Spectroscoy, 18-21 October, 1989, Pasadena, California, U.S.A.

 

14.           G. C. Stocco, F. Gattuso, A. A. Isab, and C. F. Shaw III, "Synthesis and Characterization of Complexes of Trialkyl- and Triarylphosphine Gold(I) with Thiolated Purines and Pyrimidines. A Class of Bifunctional Compounds with Potential Antitumor Activity", Fifth International Conference on Bioinorganic Chemistry, 4-10 August, 1991, Oxford, U.K. Abstract No. P023 in the J. Inorg. Biochem., Vol. 43, 1991.

 

15.           A. A. Isab, M. N. Akhtar and A. R. Al-Arfaj, "13C NMR Studies of the Redox Reactions of Aurothiomalate and Bis Aurothiomalate with Selenocyanate in an Aqueous Solution", The Third InternationalConference on Gold and Silver in Medicine, Aug. 18-20, 1994, University of Wisconsin, Milwaukee, WI, USA. Metal Based Drugs,   Vol. 1, No. 5-6 (1994), page 512.

 

16.           M. N. Akhtar, A. A. Isab, A. R. Al-Arfaj and M. I. M. Wazeer, "15N and 31P NMR Studies of Cyano (trialkyl/Triaryl) Phosphine Gold(I) Complexes R3PAu13C15N.", The Third International Conference on Gold and Silver in Medicine, Aug. 18-20, 1994, University of Wisconsin, Milwaukee, WI, USA. Metal Based Drugs,  Vol. 1, No. 5-6 (1994), page 514.

 

17.           A. Jagariamudi, A. A. Isab, C. F. Shaw III and A. Munoz, "Formation and Reactivity of [Au(13CN)4]-, [Au(13CN)3Cl]-, and [Au(13CN)3(SR)]-. Studied by 13C NMR Spectroscopy", The Third International Conference on Gold and Silver in Medicine, Aug. 18-20, 1994, University of Wisconsin, Milwaukee, WI, USA, Metal Based Drugs,  Vol. 1, No. 5-6 (1994), page 515.

 

18.           A. A. Isab, C. F. Shaw III and A. Munoz, "Exchange Reactions Between Albumin-Gold(I)-Triethylphosphine and Me3PAuCl or iPr3PAuCl Studied by 31P NMR Spectroscopy",  The Third International Conference on Gold and Silver in Medicine, Aug. 18-20, 1994, University of Wisconsin, Milwaukee, WI, USA, Metal Based Drugs,  Vol. 1, No. 5-6 (1994),  page 516.

19.           A. A. Isab, "Complexation of Selenocysteamine, Selenocysteine, and Selenoacetic acid with gold(I) thiomalate (an antiarthritic drug) studies by 13C NMR spectroscopy in aqueous solution", 210th American Chemical Society National Meeting, Aug. 20-25, 1995, Chicago, USA, Paper # 572.

20.                A.  R.  Al-Arfaj,  A. A. Isab,  M.  S.  Hussain  and  M.  N.  Akhtar  “Synthesis and spectroscopic characterization of (trialkyl/triaryl) phosphine gold(I) thiocyanate complexes” 212th American Chemical    Society    National Meeting, Aug. 25-29, 1996, Orlando, USA.

 

21.            A.  R.  Al-Arfaj, M.  N.  Akhtar and  A. A. Isab “Synthesis, spectroscopic characterization and  redistribution study of  R3PAu13C15N and R3PAuS13C15N complexes” Third International Conference on Chemistry in Industry, Nov. 18-20, 1996, Bahrain.

 

22.           A. A. Isab, M.  N.  Akhtar and A.  R.  Al-Arfaj, “Steric and Electronic control of Ligand Disproportionation in [R3PAu13C15N] complexes: 13C, 15N and 31P NMR Studies” 213th American Chemical Society National Meeting, Sep. 7-11, 1997, Las Vegas, USA.

23.                L. G. Marzilli, S. O. Ano, F. P. Intini, A. A. Isab,  and G. Natile, “Slowing the clock in Pt Anticancer Drug Chemistry” XXXIII Intl. Conf. on Coord. Chem.; The Chemistry of Metal Ions in Everyday Life, Aug 30-Sep. 4, 1998, Centro Congressi e Centro Affari Firenze, Firenze, Italy.

24            A. A. Isab, “Cis-Pt as an Anticancer Drug” Saudi Arabian International Chemical Sciences Chapter of American Chemical Society, Sept. 28, ’99, Dhahran International Hotel, Dhahran, Saudi Arabia (Invited Lecture).

25.                 M. N. Akhtar, A. A. Isab,  and A. Hassana, “Synthesis and Characterization of R3PAu13C15N complexes using multinuclear  (13C, 15N and 31P) NMR and TG/DTA Techniques” 4th International Conference and Exhibition on Chemistry and Industry, Oct.30-Nov. 01, 2000, Gulf Hotel, Manama, Bahrain.

26.                 A. A. Isab, “Some Transition Metals in Medicine” 1st Saudi Science Conference (Paper No. 14),  April 9-11, ,p 183-187, 2001, King Fahd Univ. of Petroleum and Minerals, Dhahran, Saudi Arabia.

27.           M. N. Akhtar, A. A. Isab  and S. Ahmad “Synthesis and  Characterization  of Trialkyl/Aryl Phosphine Sulfide Gold(I) Complexes” 5th International Conference and Exhibition on Chemistry and Industry, 14-16 Oct., 2002, Gulf Hotel, Manama, Bahrain. (Paper No. ANA-P2 Analytical Chemistry Session).

 

28..          A. A. Isab, W. Ashraf,  S. Ahmad and M. I. M. Wazeer, “31P and 13C NMR studies of the redox and exchange reactions of gold(I) drugs with disulfides and diselenides” 2nd Saudi Science Conference, 15-17 March, 2004, Jeddah, Saudi Arabia. (Paper No. CHEM 237).

 

29.                 M. I. M. Wazeer, A. A. Isab, A. El Rayyes, H. P. Perzanowski, “Solid-state NMR studies and Molecular Computations of 1,3 imidazolidine-2-thione, 1,3-imidazolidine-2-selenone and some related compounds”  2nd Suadi Science Conference, 15-17 March, 2004, Jeddah, Saudi Arabia. (Paper No. CHEM 247)

30.                  A. A. Isab, W. Ashraf, and M. I. M. Wazeer, “Redox and Exchange Reactions Gold (I) Drugs with Disulphide and Diselenide in Aqueous Solutions” 228th American Chemical Society (Paper No. 733), 22-26, August 2004, Philadelphia, USA.

31.           M. I. M. Wazeer and A. A. Isab,  “Solid-state NMR study of the S and Se analogues of urea complex with        d10 metal ions”  6th International Conference and Exhibition on Chemistry and Industry, 27-29 Sept., 2004, Gulf Hotel, Manama, Bahrain.

32.           M. N. Akhtar , A. A. Isab and  S. Ahmad, “13C AND 15N NMR Studies of the  Interaction of Gold(I)

                Based Medicines with Thiourea ” 6th International Conference and Exhibition on Chemistry and Industry, 27-29 Sept., 2004, Gulf Hotel, Manama, Bahrain.

33.                 A. A. Isab, W. Ashraf, and M. I. M. Wazeer, “Redox and Exchange Reactions Gold (I) Drugs with Disulphide and Diselenide in Aqueous Solutions” 6th International Conference and Exhibition on Chemistry and Industry, 27-29 Sept., 2004, Gulf Hotel, Manama, Bahrain.

34.                 M. I. M. Wazeer and A. A. Isab,  “Multinuclear Solid-state and solution NMR studies of Silver Complexes of some Substituted Ureas”  7th International Conference and Exhibition on Chemistry and Industry, 26-28 March, 2007, Gulf Hotel, Manama, Bahrain.

35.                 A. A. Isab, M. I. M. Wazeer and Bassem A.-Al-Mayt " Solution as well as solid NMR studies on 1:1 and 2:1 adducts of silver(I) cyanide with alkanediamine ligands" 233rd ACS National Meeting, March 25-29, 2007, Chicago, IL, USA

36.           S. Ahmad, M. Hanif, M. Monim-ul-, Mehboob, A. A. Isab, S. Ahmad, " Silver(I) complexation with      glutathione and tetramethylthiourea",13th International Conference, 15-20 July, (2007) Vienna,     Austria. Abstract published in J. Biol. Inorg.  Chem. (2007) 12 (Suppl 1):S123.