Syllabus
Home Teaching Research Medical Physics

 

 

Course Title

:

Magnetic Resonance Imaging (MRI)

Course Code

:

MEPH 568

Credit Hours

:

2

Prerequisite

:

Graduate Standing

     

Course Description

Physics and technology of magnetic resonance imaging (MRI), emphasizing techniques employed in medical diagnostic imaging. Major topics: physics of MR, pulse sequences, hardware, imaging techniques, artifacts, and spectroscopic localization.

 

Main Textbook

Magnetic Resonance Imaging: Physical Principles and Sequence Design.  E.M. Haacke, R.W. Brown, M.R. Thompson, and R. Venkatesan.  First edition, 1999.  John Wiley & Sons, Inc.

 

References

* MRI from Picture to Proton.  McRobbie et al

 

* Magnetic Resonance Imaging: Physical and Biological Principles.  Bushong

 

* Principles of Magnetic Resonance Imaging: A Signal Processing Perspective.  Liang and Lauterbur.

 

* Magnetic Resonance Imaging: Physical Principles and Applications.  Kuperman.

 

 

Teaching Tools

* Computer presentations

* Blackboard

* Transparencies

* Internet online courses

* Group discussions

* Visit to MRI department at a local hospital

 

Assessment

Activity Weight
Problem Sets 10%
Exam #1 30%
Exam #2 30%
Final Exam 30%

 

Grading

Grade

Mark

A+ ≥89
A 82-88
B+ 75-81
B 68-74
C+ 61-67
C 54-60
D+ 47-53
D 40-46
F <40

 

Course Content

Session Topic
1.

An Overview of MRI Concepts

2.

A Review of the Hardware of MRI Scanner

3.

Classical Mechanical Description of MRI

4.

Rotating Reference Frames and Resonance

5.

Bloch Equation

6.

Quantum Mechanical Basis of Precession

7.

Quantum Mechanical Basis of Relaxation

8.

Principles of MR Signal Detection

9.

Pulse Sequences.  Free Induction Decay

10.

Spin Echo, Inversion Recovery, and Spectroscopy

11.

Frequency Encoding and the Fourier Transform

12.

Gradient Echo and k-Space Diagrams

13.

Multi-Dimensional Imaging and Slice Selection

14.

2D, 3D, and Chemical Shift Imaging

15.

Continuous and Discrete Fourier Transforms

16.

Sampling, Aliasing, and the Nyquist Criterion

17.

Image Reconstruction and Artifacts

18.

Fourier Transform Image Reconstruction

19.

Filters and Point Spread Function

20.

Spatial Resolution

21.

Signal-to-Noise Ratio

22.

Contrast-to-Noise Ratio

23.

Chemical Shift in Spectroscopic Imaging

24.

Fast Imaging Techniques

25.

Echo Planar Imaging

26.

MRI Applications: Angiography, Perfusion Imaging, Diffusion Imaging, Cardiac Imaging

(Visit to MRI clinic at a local hospital)

27.

Biological Effects of MRI and Safety Considerations

28.

Review of Selected Topics