Publications
 

 

Representative Publications/Patent

Patents

1.  M. Sharif, R. Jackstell, S. Dastgir, B. Al-Shihi, M. Beller. Catalytic ligand complexes and butadiene-carbon dioxide telomerisation processes to mediate chemical transformations.

UK Pat. Appl. GB1609314.8. 2016

 2.  One patent has already been filed on role of Bromohexine and Ambroxol derivatives on FABRY and PUMPE diseases.: ROLFS, Arndt et al. R 10008 EP. 2013

 

Publications

1. M. Sharif,* R. Jackstell, S. Dastgir, B. Al-Shihi, M. Beller  ChemCatChem 2016 Accepted. Efficient synthesis of lactone by telomerization of 1,2-Butadiene with CO2.

2. M. Sharif, K. Shoaib, S.Ahmed, J. Iqbal, Z. A. Abilov, A. Spannenberg, P. Langer. Tetrahedron Lett. 2016, 57, 3060-3062. Suzuki-Miyaura reactions of 3,5-dichloro-2,4,6- source.

3. M. Sharif, X-F. Wu*. RSC Adv. 2015, 5, 21001-21004. Palladium-catalyzed synthesis of primary benzamides from ary bromides via cyanation and hydration sequence.

4. M. Sharif, ± L. He, ±  H. Neumann, M. Beller,* X-F. Wu,* Green Chem. 2014, 16, 3763-3767. A novel and convenient palladium-catalyzed synthesis of 4(3H)-quinazolinones from 2-bromoformanilides and organo nitros with Mo(CO)6 as a multiple promoter.

   5. M. Sharif, J. Chen, P. Langer, M. Beller,* X-F. Wu,* Org. Biomol. Chem. 2014, 12, 6359-6362. TBAI-Catalyzed oxidative synthesis of benzamides from aectophenones and carbinols.

    6. M. Sharif, J-b. Feng, P. Langer, M. Beller,* X-F. Wu,* Chem. Commun. 2014, 50, 4747-4750. A novel oxidative procedure for the synthesis of benzamides from styrenes and amines under metal-free Conditions.

    7. M. Sharif, A. Pews–Davtyan, J. Lukas, J. Schrank, P. Langer, A. Rolfs,* Matthias Beller,* Eur. J. Org. Chem. 2014, 222–230. Palladium–Catalysed Carbonylative Transformations of Bromhexine to New Bioactive Compounds as Glucocerebrosidase Inhibitors.

 8. M. Sharif, J. Opalach, P. Langer,  M. Beller,* Xiao-Feng Wu,* RSC Adv. 2014, 15, 1956-1961. Oxidative Synthesis of Quinazolinones and Benzothiadiazine 1,1-Dioxides from 2-Aminobenzamide and 2-Aminobenzenesulfonamide with Benzyl Alcohols and Aldehydes.

 

  

Full List of Publications, workshops and conferences:

 Publications: 33 Published, 5 submitted/ to be submitted. (** The authors have equal contribution)

 38. M. Sharif,* K. Shoaib, S. Ahmed, S. Reimann, J. Iqbal, A. Spannenberg, M. A. Hashmi, K. Ayub, P. Langer*. EJOC Revisions. Synthesis of functionalized fluorinated pyridine derivatives by site-selective Suzuki-Miyaura cross-coupling reactions of halogenated pyridines.

37. M. Sharif,* S. Iqbal, J. Iqbal, P. Langer*. Submitted Suzuki-Miyaura coupling reactions of Fluorinated Substrates.

36. M. Sharif,* S. Ahmed, K. Shoaib, J. Iqbal, A. Spannenberg, P. Langer. Submitted. Synthesis of fluorinated alkynyl pyridines by copper free palladium catalyzed sonogashira couplings reactions.

35. M. Sharif, A. Börner Manuscript in prepration 2016. Synthesis of new phosphite ligand and their catalytic applications in hydroformylation of Styrene.

34. M. Sharif,* R. Jackstell, S. Dastgir, B. Al-Shihi, M. Beller ChemCatChem 2016 Accepted.

33. M. Sharif, K. Shoaib, S.Ahmed, J. Iqbal, Z. A. Abilov, A. Spannenberg, P. Langer. Tetrahedron Lett. 2016, 57, 3060-3062. Suzuki-Miyaura reactions of 3,5-dichloro-2,4,6-trifluoropyridines.

32. R. U. Nissa, Z. Sugheer, M. A. Hashmi, M. Sharif, M. A. Gilani, R. Ludwig, T. Mahmood, J. Iqbal, K. Ayub. Polyhedron 2016, 112, 34-42. Theoretical mechanistic investigation of Zin(II) catalyzed oxidative amidation of benzyl alcohols with amines.

31. K. Natte, R. V. Jagadeesh, M. Sharif, H. Neumann, M. Beller Org. Biomol. Chem., 2016, 14, 3356-3359. Synthesis of Nitriles from Amines using Nanoscale Co3O4-based catalysts.

30. S. Reimann, P. Ehlers, M. Sharif, A. Spannenberg, P. Langer*. Tetrahedron 2016, 72, 1083-1094. A general protocol for the efficient synthesis of polyarylated benzenes by multiple Suzuki-Miyaura reactions of polychlorinated benzenes

29. A. Maalik, M. Sharif, N. Abbass, A. Spannenberg, A. Villinger, P. Langer*. Tetrahedron 2016, 72, 1076-108. Synthesis of Tetra and Pentaaryl Fluorobenzenes by Suzuki-Miyaura coupling reactions and their photophysical properties.

28. S. Reimann, S. Parpart, P. Ehlers, M. Sharif, A. Spannenberg, P.Langer*. Org. Biomol. Chem. 2015, 13, 6832-6838. Synthesis of Tetraarylpyridines by chemo-selective Suzuki-Miyaura reactions.

27. X-F. Wu*, St. Oschatz, M. Sharif, P. Langer*. Synthesis 2015, 47, A-F. Palladium- catalyzed carbonylative synthesis of N-benzoylindoles with Mo(CO)6 as carbon monoxide source. 4 | P a g e

 

26. M. Sharif, X-F. Wu*. RSC Adv. 2015, 5, 21001-21004. Palladium-catalyzed synthesis of primary benzamides from ary bromides via cyanation and hydration sequence.

25. J.Lukas, A-M. Pockrandt, S. Seemann, M. Sharif, F. Runge, S. Pohler, C. Zheng, A. Gläser, A-K. Giese, M. Beller, A. Rolfs,* Molecular Therapy 2015, Online published. Enzyme enhancers for the treatment of Fabry and Pompe Disease.

24. M. Sharif, ± L. He, ± H. Neumann, M. Beller,* X-F. Wu,* Green Chem. 2014, 16, 3763-3767. A novel and convenient palladium-catalyzed synthesis of 4(3H)-quinazolinones from 2-bromoformanilides and organo nitros with Mo(CO)6 as a multiple promoter.

23. M. Sharif, J. Chen, P. Langer, M. Beller,* X-F. Wu,* Org. Biomol. Chem. 2014, 12, 6359-6362. TBAI-Catalyzed oxidative synthesis of benzamides from aectophenones and carbinols.

22. M. Sharif, J-b. Feng, P. Langer, M. Beller,* X-F. Wu,* Chem. Commun. 2014, 50, 4747-4750. A novel oxidative procedure for the synthesis of benzamides from styrenes and amines under metal-free Conditions.

21. J. Lukas, A-M. Pockrandt, S. Seemann, F. Runge, C. Zheng, M. Sharif, A. Pews-Devtyan, M. Beller, V. Saviouk, A-K. Giese, A. Rolfs,* Mol.Gen.& Met. 2014, 2, S73. Small molecul enhancers for the mutant enzymes in lysosomal disorders.

20. M. Sharif, A. Pews-Devtyan, P. Langer, A. Rolfs,* M. Beller* Tetrahedron 2014, 5128-5135. First Palladium-Catalyzed Suzuki-Miyaura Coupling Reactions of Bromohexine and Ambroxol

19. X-F. Wu*, S. Oschatz, M. Sharif, M. Beller, P. Langer,* Tetrahedron 2014, 23-29. Palladium-catalyzed carbonylative synthesis of N-(2 cyanoaryl)benzamides and sequential synthesis of quinazolinones

18. M. Sharif, A. Pews–Davtyan, J. Lukas, J. Schrank, P. Langer, A. Rolfs,* Matthias Beller,* Eur. J. Org. Chem. 2014, 222–230. Palladium–Catalysed Carbonylative Transformations of Bromhexine to New Bioactive Compounds as Glucocerebrosidase Inhibitors.

17. M. Sharif, J. Opalach, P. Langer, M. Beller,* Xiao-Feng Wu,* RSC Adv. 2014, 15, 1956-1961. Oxidative Synthesis of Quinazolinones and Benzothiadiazine 1,1-Dioxides from 2-Aminobenzamide and 2-Aminobenzenesulfonamide with Benzyl Alcohols and Aldehydes.

16. X-F. Wu,* M. Sharif, J-b. Feng, H. Neumann, A. Pews-Davtyan, P. Langer, Matthias Beller,* Green Chem. 2013, 15, 1956-1961. A General and Practical Oxidation of Alcohols to Primary Amides under Metal-Free Conditions

15. M. Sharif, A. Maalik, S. Reimann, J. Iqbal, T. Patonay, A. Villinger, A. Spannenberg, P. Langer,* Tetrahedron 2013, 69, 174-183. Synthesis and Photophysical Properties of Tetra- and Pentaalkynyl Fluorobenzenes.

14. X-F. Wu,* M. Sharif, H. Neumann, A. Pews-Davtyan, P. Langer, M. Beller,* Eur. J. Org. Chem. 2013, 2783–2787. Zn(II)-Catalyzed Oxidative Amidation of Benzyl alcohols With Amines under Solvent-free Condition.

13. X-F. Wu,* S. Oschatz, M. Sharif, A. Flader, L. Krey, M.Beller, P. Langer,* Adv. Syn. Cat. 2013, 18, 3581–3585. Palladium-Catalyzed Carbonylative Synthesis of Phthalimides from 1,2-Dibromoarenes with Mo(CO)6 as CO source.

12. S. Reimann, K. Wittler, S. Schmode, M. Sharif, A. Spannenberg, R. Ludwig, P. Langer,* Eur. J. Org. Chem. 2013, 8115–8134. Site-Selective Sonogashira Reactions of 1,4-Dibromo-2-(trifluoromethyl)benzene – Synthesis and Properties of Fluorinated Alkynylbenzenes.

11. X-F. Wu,* M. Sharif, K. Shoaib, H. Neumann, A. Pews-Davtyan, P. Langer, M. Beller,* Chem. Eur. J. 2013, 19, 6230-6233.

10. S. Ahmed, M. Sharif,* K. Shoaib, S. Reimann, J. Iqbal, A. Spannenberg, P. Langer,* Tetrahedron Lett. 2013, 54, 1669-1672. Synthesis of 2,6-Diaryl-3-(trifluoromethyl)pyridines by Site-Selective Suzuki-Miyaura Reactions of 2,6-Dichloro-3-(trifluoromethyl)pyridine. 5 | P a g e

 

09. M. Sharif, A. Maalik, S. Reimann, J. Iqbal, T. Patonay, A. Villinger, P. Langer,* J. Fluorine Chem. 2013, 146, 19-36. Synthesis of Functionalized Fluorinated Terphenyls by Site-Selective Suzuki-Miyaura Cross-Coupling Reactions of Dibrominated Fluorbenzenes.

08. S. Reimann, A. Bunescu, A. Petrosyan, M. Sharif, S.Erfle, . Mamat, T. V. Ghochikyan, A. S. Saghyan, A. Spannenberg, A. Villinger, Peter Langer,* Helvetica Chimica Acta 2013, 96, 1955-1967. Regioselective Synthesis of Trichloromethyl-Substituted Salicylates and Cyclohexenones by One-Pot Cyclizations of 1,3-Bis-(trimethylsilyloxy)-1,3-butadienes.

07. S. Reimann,± M. Sharif,± K. Wittler, L. R. Knöpke, A-E. Surkus, C. Roth, R. Ludwig, T. Patonay, P. Langer,* Z. Naturforsch. 2013, 68b, 367 – 377 / DOI: 10.5560/ZNB.2013-3004.

06. S. Reimann, M. Sharif, M. Hein, A. Villinger, K.Wittler, R. Ludwig, P. Langer,* Eur. J. Org. Chem. 2012, 604-615. Site-Selective Sonogashira Reactions of 1,4-Dibromo-2-fluorobenzene. Synthesis and Properties of Fluorinated Alkynylbenzenes.

05. S. Reimann, P. Ehlers, M. Sharif, K. Wittler, R. Ludwig, A. Spannenberg, P. Langer,* Catalysis Commun. 2012, 25, 142-147. Site-Selective Sonogashira Reactions of 1,2-Dibromo-3,5 difluorobenzene.

04. M. Sharif, S. Reimann, K.Wittler, L. R. Knöpke, A-E. Surkus, C. Roth, A. Villinger, R.Ludwig,* P. Langer,* Eur. J. Org. Chem. 2011, 5261-5271. 1-(Arylalkenyl)pyrenes: Synthesis, Structure, Photophysical, Theoretical and Electrochemical Investigations.

03. M. Sharif, S. Reimann, A. Villinger, P. Langer,* Synlett 2010, 913-916. One-Pot Synthesis of Difluorinated ortho-Terphenyls by Site-Selective Suzuki-Miyaura Reactions of 1,2-Dibromo-3,5-difluorobenzene”.

02. M. Sharif, M. Zeeshan, S. Reimann, A. Villinger, P.Langer,* Tetrahedron Lett. 2010, 51, 2810-2812. One-Pot Synthesis of Fluorinated Terphenyls by Site-Selective Suzuki-Miyaura Reactions of 1,4-Dibromo-2-fluorobenzene.

01. M.Hussain, D. S. Zinad, G. A. Salman, M. Sharif, A. Villinger, P. Langer,* Synlett. 2010, 276-280. Efficient Synthesis of Functionalized Anthraquinones by Domino Twofold Heck / 6p-Electrocyclization Reactions of 2,3-Dibromonaphthoquinone.

±; Authors have equal contribution

Conferences and workshops:

13. Poster presentation at ICC16 Beiging China 3-8th July 2016

12. Oral/poster presentation at Carbon Dioxxide Conference, Albufeira Purtigal 19-22 April 2016

11. Seminar on Green and Organometallic catalysis at Deptt. of Chemistry, College of Science

Sultan Qaboos University Muscat Oman 09th Nov 2015

10. Seminar on Hydroformylation at Evonik Industries Germany 01st October 2015

09. Seminar at Deptt. of Chemistry King Fahd University of Petroleum and Minerals Saudi Arabia

16th September 2015

08. Workshop on Road map for catalysis center at QEERI Qatar 13th-14th September 2015 at

DOHA, Qatar

07. Poster presentation in IUPAC 48th World Chemistry Congress 09th-14th August 2015

06. Oral and poster presentation in Three-Days International Conference 21st-23rd January 2015

Exploring new avenues in Medicinal chemistry opportunities and challenges. Department of

Chemistry Forman Christian College (Charterd University) Lahore Pakistan

05. Participated and poter presentation in 8th Asian-European Metal-Mediated Efficient Organic

Synthesis Symposium (07-11th September 2014) at Department of Chemistry Izmir Institute of

Technology Izmir, Turkey 6 | P a g e

 

04. Organizer and Participant in 14th JCF-Frühjahrssymposium 18th-21th March 2012, Rostock

03. Seminar/Talk on “Synthesis of Fluorinated Arenes and Bromhexin/Ambroxol derivatives by

metal catalyzed cross coupling reactions” 04th September 2012 at Allama Iqbal Open

University Pakistan

02. Participated in 5th International and 15th National Chemistry Conference (24-27th November

2004) at Department of Chemistry Quaid-i-Azam University Islamabad Pakistan

01. Attended and Participated in workshop on Combinatorial Chemistry by Prof. J. Rademann of

University of Berlin, Germany from May 7-13th May, 2004

 

 



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